ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: pleckstrin homology domain containing, family G (with RhoGef domain) member 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000008323 PLEKHG6 9606 + 12:6310436-6328506 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000011684 PLEKHG6-001 6310436-6328505 protein_coding
  ENST00000304581 PLEKHG6-005 6319460-6328506 protein_coding
  ENST00000396988 PLEKHG6-003 6310933-6328505 protein_coding
  ENST00000449001 PLEKHG6-004 6312651-6328485 protein_coding
  ENST00000535616 PLEKHG6-008 6318743-6319206 processed_transcript
  ENST00000536531 PLEKHG6-002 6310738-6318973 protein_coding
  ENST00000538208 PLEKHG6-007 6310810-6312523 processed_transcript
  ENST00000543000 PLEKHG6-009 6317567-6318363 processed_transcript
  ENST00000544743 PLEKHG6-006 6318763-6319595 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000011684ENST00000304581ENST00000449001ENST00000536531ENST00000543000
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000011684 0.016±0.00 0.359±0.56 0.112±0.00 N/A 0.030±0.01
ENST00000304581 0.059±0.00 0.318±0.21 0.254±0.00 0.285±0.00 0.102±0.07
ENST00000449001 N/A 0.017±0.00 N/A N/A 0.022±0.01
ENST00000536531 N/A 1.369±0.25 N/A N/A 0.080±0.03
ENST00000543000 N/A N/A N/A N/A 2.068±0.00

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005096 IEA GTPase activator activity
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0005856 IEA cytoskeleton
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0035023 IEA regulation of Rho protein signal transduction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000038167 Plekhg6 protein_coding Mus_musculus

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