ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: microsomal glutathione S-transferase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000008394 MGST1 9606 + 12:16347142-16609259 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000010404 MGST1-201 16347142-16364409 protein_coding
  ENST00000359720 MGST1-016 16382827-16438761 processed_transcript
  ENST00000396207 MGST1-002 16353417-16364409 protein_coding
  ENST00000396209 MGST1-202 16347778-16364409 protein_coding
  ENST00000396210 MGST1-001 16347649-16364403 protein_coding
  ENST00000534835 MGST1-008 16347645-16349106 processed_transcript
  ENST00000535309 MGST1-004 16347694-16377192 protein_coding
  ENST00000535624 MGST1-011 16357511-16364260 retained_intron
  ENST00000536371 MGST1-005 16347142-16363806 protein_coding
  ENST00000537878 MGST1-012 16347654-16354724 retained_intron
  ENST00000538857 MGST1-015 16354231-16589580 processed_transcript
  ENST00000538885 MGST1-009 16350746-16354378 protein_coding
  ENST00000539036 MGST1-017 16347652-16609259 processed_transcript
  ENST00000539708 MGST1-010 16347664-16364060 processed_transcript
  ENST00000540056 MGST1-007 16347778-16364071 protein_coding
  ENST00000540126 MGST1-006 16347797-16363814 protein_coding
  ENST00000542256 MGST1-003 16347654-16370408 processed_transcript
  ENST00000543076 MGST1-013 16347645-16363999 protein_coding
  ENST00000624056 MGST1-014 16362568-16364409 TEC

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000010404ENST00000396207ENST00000396210ENST00000535624ENST00000536371ENST00000543076
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000010404 N/A 11.659±5.97 N/A N/A N/A
ENST00000396207 19.612±0.00 N/A N/A N/A N/A
ENST00000396210 30.025±11.04 37.772±27.95 8.835±0.00 99.101±0.00 65.149±37.29
ENST00000535624 N/A N/A N/A N/A 5.299±0.00
ENST00000536371 N/A N/A N/A N/A 162.474±40.28
ENST00000543076 N/A 44.034±33.73 N/A N/A 53.670±52.16

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0007NM CIL_0007NM_0001 UCNEbase
CIL_00098O CIL_00098O_0001 VISTA
CIL_0005FD CIL_0005FD_0001 CGP
CIL_0009BE CIL_0009BE_0001 VISTA
CIL_0005FE CIL_0005FE_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004364 IDA glutathione transferase activity
GO:0004602 IDA glutathione peroxidase activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005739 IDA mitochondrion
GO:0005741 IEA mitochondrial outer membrane
GO:0005743 IEA mitochondrial inner membrane
GO:0005778 ISS peroxisomal membrane
GO:0005783 ISS endoplasmic reticulum
GO:0005789 TAS endoplasmic reticulum membrane
GO:0006749 IEA glutathione metabolic process
GO:0006805 TAS xenobiotic metabolic process
GO:0010243 IEA response to organonitrogen compound
GO:0016021 ISS integral component of membrane
GO:0032496 IEA response to lipopolysaccharide
GO:0033327 IEA Leydig cell differentiation
GO:0042493 IEA response to drug
GO:0042802 IEA identical protein binding
GO:0042803 IEA protein homodimerization activity
GO:0043295 IEA glutathione binding
GO:0044281 TAS small molecule metabolic process
GO:0045177 IEA apical part of cell
GO:0055114 IDA oxidation-reduction process
GO:0070207 ISS protein homotrimerization
GO:0071449 IDA cellular response to lipid hydroperoxide
GO:1901687 TAS glutathione derivative biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000022165 mgst1.2 protein_coding Danio_rerio
ENSDARG00000032618 mgst1.1 protein_coding Danio_rerio
ENSMUSG00000008540 Mgst1 protein_coding Mus_musculus

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