ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: snail family zinc finger 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000019549 SNAI2 9606 - 8:48917690-48921740 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000020945 SNAI2-201 48917690-48921440 protein_coding
  ENST00000396822 SNAI2-001 48917768-48921740 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000020945ENST00000396822
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000020945 3.347±0.28 0.926±0.84 4.077±0.00 5.766±0.00 0.476±0.82
ENST00000396822 N/A 0.302±0.04 N/A N/A 0.239±0.06

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000790 IDA nuclear chromatin
GO:0001078 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0001649 IEP osteoblast differentiation
GO:0001837 IMP epithelial to mesenchymal transition
GO:0003198 ISS epithelial to mesenchymal transition involved in endocardial cushion formation
GO:0003273 ISS cell migration involved in endocardial cushion formation
GO:0003682 IEA chromatin binding
GO:0003705 IEA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IEA cytoplasm
GO:0006366 IEA transcription from RNA polymerase II promoter
GO:0006933 IEA negative regulation of cell adhesion involved in substrate-bound cell migration
GO:0007219 IMP Notch signaling pathway
GO:0007605 IMP sensory perception of sound
GO:0009314 IEA response to radiation
GO:0010839 IDA negative regulation of keratinocyte proliferation
GO:0010957 IDA negative regulation of vitamin D biosynthetic process
GO:0014032 IMP neural crest cell development
GO:0016477 IEA cell migration
GO:0030335 IMP positive regulation of cell migration
GO:0032331 IMP negative regulation of chondrocyte differentiation
GO:0032642 IMP regulation of chemokine production
GO:0033629 IC negative regulation of cell adhesion mediated by integrin
GO:0035066 IEA positive regulation of histone acetylation
GO:0035414 IDA negative regulation of catenin import into nucleus
GO:0035921 IMP desmosome disassembly
GO:0043066 IEA negative regulation of apoptotic process
GO:0043473 IMP pigmentation
GO:0043518 IMP negative regulation of DNA damage response, signal transduction by p53 class mediator
GO:0043565 IDA sequence-specific DNA binding
GO:0044344 IEA cellular response to fibroblast growth factor stimulus
GO:0045600 IEA positive regulation of fat cell differentiation
GO:0045667 IMP regulation of osteoblast differentiation
GO:0046872 IEA metal ion binding
GO:0050872 IEA white fat cell differentiation
GO:0060021 IEA palate development
GO:0060070 IMP canonical Wnt signaling pathway
GO:0060429 ISS epithelium development
GO:0060536 IEA cartilage morphogenesis
GO:0060693 IEA regulation of branching involved in salivary gland morphogenesis
GO:0070563 IDA negative regulation of vitamin D receptor signaling pathway
GO:0071364 IDA cellular response to epidermal growth factor stimulus
GO:0071479 IEA cellular response to ionizing radiation
GO:0090090 IDA negative regulation of canonical Wnt signaling pathway
GO:1900387 IMP negative regulation of cell-cell adhesion by negative regulation of transcription from RNA polymerase II promoter
GO:1902230 IMP negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:2000647 IEA negative regulation of stem cell proliferation
GO:2000810 IMP regulation of tight junction assembly
GO:2000811 IMP negative regulation of anoikis
GO:2001240 ISS negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000040046 snai2 protein_coding Danio_rerio
ENSMUSG00000022676 Snai2 protein_coding Mus_musculus

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