ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: cholinergic receptor, nicotinic, alpha 3 (neuronal)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000080644 CHRNA3 9606 - 15:78593052-78621295 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000326828 CHRNA3-001 78595305-78621179 protein_coding
  ENST00000348639 CHRNA3-002 78593052-78621295 protein_coding
  ENST00000558903 CHRNA3-008 78601776-78607524 processed_transcript
  ENST00000559002 CHRNA3-004 78593052-78596732 processed_transcript
  ENST00000559080 CHRNA3-007 78618630-78619278 protein_coding
  ENST00000559658 CHRNA3-003 78593052-78620863 nonsense_mediated_decay
  ENST00000559941 CHRNA3-006 78618849-78620261 processed_transcript
  ENST00000561128 CHRNA3-005 78618380-78620789 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DENST00000326828ENST00000559002ENST00000559658
Transcript ID BECs HAoEC HMVEC-D
ENST00000326828 N/A 0.986±0.25 N/A
ENST00000559002 N/A N/A 3.258±0.00
ENST00000559658 0.250±0.00 1.174±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0003TW CIL_0003TW_0001 CGP
CIL_0003TT CIL_0003TT_0001 CGP
CIL_0001KZ CIL_0001KZ_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004889 TAS acetylcholine-activated cation-selective channel activity
GO:0005230 IEA extracellular ligand-gated ion channel activity
GO:0005515 IEA protein binding
GO:0005886 TAS plasma membrane
GO:0005892 IDA acetylcholine-gated channel complex
GO:0006810 IEA transport
GO:0006811 NAS:IEA ion transport
GO:0006812 TAS cation transport
GO:0006937 IEA regulation of muscle contraction
GO:0006940 ISS regulation of smooth muscle contraction
GO:0007165 IDA signal transduction
GO:0007171 ISS activation of transmembrane receptor protein tyrosine kinase activity
GO:0007268 TAS synaptic transmission
GO:0007271 ISS synaptic transmission, cholinergic
GO:0007399 IMP nervous system development
GO:0007626 ISS locomotory behavior
GO:0014056 ISS regulation of acetylcholine secretion, neurotransmission
GO:0014069 ISS postsynaptic density
GO:0015276 TAS ligand-gated ion channel activity
GO:0015464 IDA acetylcholine receptor activity
GO:0016020 IEA membrane
GO:0016021 NAS:IEA integral component of membrane
GO:0030054 IEA cell junction
GO:0030425 ISS dendrite
GO:0034220 TAS ion transmembrane transport
GO:0035095 IMP behavioral response to nicotine
GO:0042166 IC acetylcholine binding
GO:0042391 ISS regulation of membrane potential
GO:0043025 ISS neuronal cell body
GO:0045211 IEA postsynaptic membrane
GO:0048814 ISS regulation of dendrite morphogenesis
GO:0060079 ISS regulation of excitatory postsynaptic membrane potential
GO:0060084 IMP synaptic transmission involved in micturition
GO:0098655 IEA cation transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000032303 Chrna3 protein_coding Mus_musculus

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