ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: karyopherin alpha 1 (importin alpha 5)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000114030 KPNA1 9606 - 3:122421949-122514945 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000344337 KPNA1-001 122421949-122514928 protein_coding
  ENST00000464940 KPNA1-011 122451585-122464259 processed_transcript
  ENST00000465882 KPNA1-006 122442048-122514945 protein_coding
  ENST00000466923 KPNA1-004 122426104-122460657 processed_transcript
  ENST00000470904 KPNA1-005 122425680-122459885 processed_transcript
  ENST00000476916 KPNA1-010 122451990-122514937 protein_coding
  ENST00000482287 KPNA1-009 122451985-122514542 protein_coding
  ENST00000485027 KPNA1-003 122426954-122496637 nonsense_mediated_decay
  ENST00000493510 KPNA1-008 122453910-122514906 protein_coding
  ENST00000494339 KPNA1-002 122426985-122514934 nonsense_mediated_decay

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000344337ENST00000465882ENST00000466923ENST00000470904ENST00000494339
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000344337 1.890±0.00 6.425±1.27 2.555±0.00 9.114±0.00 4.605±2.29
ENST00000465882 N/A 12.179±0.00 N/A N/A 7.986±0.00
ENST00000466923 N/A N/A N/A N/A 3.210±0.27
ENST00000470904 3.473±0.00 15.697±3.16 2.560±0.00 14.444±0.00 8.788±3.98
ENST00000494339 N/A 10.901±1.62 N/A N/A 11.056±2.26

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000018 TAS regulation of DNA recombination
GO:0005488 IEA binding
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA:ISS:IEA nucleus
GO:0005643 TAS nuclear pore
GO:0005654 TAS nucleoplasm
GO:0005737 IDA:IEA cytoplasm
GO:0005829 TAS cytosol
GO:0006309 TAS apoptotic DNA fragmentation
GO:0006606 IEA protein import into nucleus
GO:0006607 TAS NLS-bearing protein import into nucleus
GO:0006915 TAS apoptotic process
GO:0006921 TAS cellular component disassembly involved in execution phase of apoptosis
GO:0008139 TAS nuclear localization sequence binding
GO:0008565 IEA protein transporter activity
GO:0016032 TAS viral process
GO:0019058 TAS viral life cycle
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0030425 ISS dendrite
GO:0042307 ISS positive regulation of protein import into nucleus
GO:0075733 TAS intracellular transport of virus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000016360 kpna1 protein_coding Danio_rerio
ENSMUSG00000022905 Kpna1 protein_coding Mus_musculus

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