ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: microtubule-actin crosslinking factor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000127603 MACF1 9606 + 1:39081316-39487177 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000289893 MACF1-005 39331138-39486987 protein_coding
  ENST00000360115 MACF1-010 39453837-39486987 protein_coding
  ENST00000361689 MACF1-001 39084167-39486987 protein_coding
  ENST00000372915 MACF1-028 39084132-39486980 protein_coding
  ENST00000372925 MACF1-003 39300314-39486987 protein_coding
  ENST00000422234 MACF1-024 39462020-39479994 protein_coding
  ENST00000442046 MACF1-007 39460747-39486987 protein_coding
  ENST00000446276 MACF1-011 39459123-39486987 protein_coding
  ENST00000462103 MACF1-026 39467750-39479880 processed_transcript
  ENST00000462496 MACF1-023 39462024-39480116 processed_transcript
  ENST00000467673 MACF1-013 39105429-39254648 retained_intron
  ENST00000469366 MACF1-015 39215265-39254440 processed_transcript
  ENST00000469490 MACF1-021 39435626-39442289 processed_transcript
  ENST00000472385 MACF1-018 39284091-39285330 retained_intron
  ENST00000473843 MACF1-020 39434485-39436007 processed_transcript
  ENST00000476350 MACF1-004 39300314-39373473 processed_transcript
  ENST00000480624 MACF1-014 39215262-39260540 processed_transcript
  ENST00000482035 MACF1-025 39414185-39428092 protein_coding
  ENST00000484393 MACF1-019 39285337-39287613 retained_intron
  ENST00000484793 MACF1-012 39081316-39102981 protein_coding
  ENST00000485063 MACF1-017 39283126-39284220 retained_intron
  ENST00000487656 MACF1-022 39452533-39453749 processed_transcript
  ENST00000494012 MACF1-016 39204695-39254375 protein_coding
  ENST00000496360 MACF1-006 39468593-39486217 processed_transcript
  ENST00000496804 MACF1-002 39268465-39327225 nonsense_mediated_decay
  ENST00000497807 MACF1-008 39468643-39486987 processed_transcript
  ENST00000497964 MACF1-009 39456706-39464909 processed_transcript
  ENST00000524432 MACF1-030 39105411-39323008 protein_coding
  ENST00000528611 MACF1-027 39328369-39331244 processed_transcript
  ENST00000530262 MACF1-029 39268527-39357775 protein_coding
  ENST00000530275 MACF1-034 39409073-39416482 protein_coding
  ENST00000564288 MACF1-032 39204246-39487177 protein_coding
  ENST00000567887 MACF1-031 39084062-39487177 protein_coding
  ENST00000602421 MACF1-033 39081417-39103726 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000289893ENST00000360115ENST00000361689ENST00000372915ENST00000372925ENST00000442046ENST00000497807ENST00000524432ENST00000530275ENST00000564288
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000289893 N/A 12.253±11.58 N/A 5.822±0.00 9.619±6.23
ENST00000360115 17.423±6.38 N/A 23.780±0.00 N/A 13.662±6.39
ENST00000361689 N/A 6.441±1.86 N/A 4.512±0.00 10.498±8.70
ENST00000372915 N/A 25.028±0.00 N/A N/A 8.098±5.62
ENST00000372925 1.967±0.00 N/A N/A N/A 4.128±3.54
ENST00000442046 38.028±1.42 N/A 23.642±0.00 N/A N/A
ENST00000497807 N/A N/A 22.619±0.00 N/A N/A
ENST00000524432 N/A 72.732±13.98 N/A N/A 51.323±25.84
ENST00000530275 N/A N/A N/A N/A 0.175±0.00
ENST00000564288 N/A N/A N/A N/A 4.502±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0008G7 CIL_0008G7_0001 VISTA
CIL_0007Q3 CIL_0007Q3_0001 VISTA
CIL_000990 CIL_000990_0001 VISTA

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001707 IEA mesoderm formation
GO:0003676 IEA nucleic acid binding
GO:0003779 IDA actin binding
GO:0005509 IEA calcium ion binding
GO:0005515 IPI:IEA protein binding
GO:0005737 ISS cytoplasm
GO:0005794 IDA Golgi apparatus
GO:0005856 NAS:IEA cytoskeleton
GO:0005874 IDA microtubule
GO:0005886 IDA plasma membrane
GO:0006200 IEA ATP catabolic process
GO:0006620 IEA posttranslational protein targeting to membrane
GO:0006928 IEA cellular component movement
GO:0007050 IEA cell cycle arrest
GO:0007163 IEA establishment or maintenance of cell polarity
GO:0008017 IEA microtubule binding
GO:0010632 ISS regulation of epithelial cell migration
GO:0015629 IEA actin cytoskeleton
GO:0015630 IEA microtubule cytoskeleton
GO:0016055 IEA Wnt signaling pathway
GO:0016887 ISS ATPase activity
GO:0030177 ISS positive regulation of Wnt signaling pathway
GO:0032587 IDA ruffle membrane
GO:0032886 IMP regulation of microtubule-based process
GO:0042060 ISS wound healing
GO:0043001 IDA Golgi to plasma membrane protein transport
GO:0044822 IDA poly(A) RNA binding
GO:0051015 NAS actin filament binding
GO:0051893 ISS regulation of focal adhesion assembly

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000028533 macf1a protein_coding Danio_rerio
ENSMUSG00000028649 Macf1 protein_coding Mus_musculus

Loading