ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000137872 SEMA6D 9606 + 15:47184101-47774223 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000316364 SEMA6D-004 47718489-47774223 protein_coding
  ENST00000354744 SEMA6D-005 47718489-47774223 protein_coding
  ENST00000355997 SEMA6D-201 47718489-47774222 protein_coding
  ENST00000358066 SEMA6D-006 47718489-47774223 protein_coding
  ENST00000389425 SEMA6D-003 47718461-47765480 protein_coding
  ENST00000389428 SEMA6D-007 47718489-47774223 protein_coding
  ENST00000536845 SEMA6D-002 47717363-47771933 protein_coding
  ENST00000537942 SEMA6D-202 47412390-47774220 protein_coding
  ENST00000558014 SEMA6D-001 47184101-47774221 protein_coding
  ENST00000558431 SEMA6D-014 47765822-47767303 retained_intron
  ENST00000558816 SEMA6D-008 47717457-47772882 protein_coding
  ENST00000559064 SEMA6D-015 47766577-47767515 protein_coding
  ENST00000559184 SEMA6D-009 47185663-47759864 protein_coding
  ENST00000559196 SEMA6D-013 47759723-47762319 protein_coding
  ENST00000560006 SEMA6D-016 47766580-47770765 protein_coding
  ENST00000560636 SEMA6D-010 47339067-47759802 protein_coding
  ENST00000561106 SEMA6D-011 47717402-47759983 retained_intron
  ENST00000561133 SEMA6D-012 47716998-47761428 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000316364ENST00000354744ENST00000355997ENST00000358066ENST00000389425ENST00000536845ENST00000537942ENST00000558014ENST00000558816ENST00000559196ENST00000561106
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000316364 N/A 0.305±0.00 N/A N/A 1.200±0.74
ENST00000354744 N/A 0.230±0.14 N/A N/A 1.270±1.26
ENST00000355997 N/A N/A N/A N/A 0.488±0.14
ENST00000358066 N/A N/A N/A N/A 0.102±0.00
ENST00000389425 N/A N/A N/A N/A 1.205±0.88
ENST00000536845 N/A 0.168±0.02 N/A N/A 1.635±1.32
ENST00000537942 N/A 0.189±0.03 0.344±0.00 N/A 0.130±0.00
ENST00000558014 N/A 0.255±0.30 N/A N/A 1.167±1.06
ENST00000558816 0.100±0.00 0.165±0.09 N/A N/A 1.511±1.33
ENST00000559196 N/A 0.545±0.00 N/A N/A N/A
ENST00000561106 N/A N/A N/A 0.472±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0004NB CIL_0004NB_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004872 IEA receptor activity
GO:0005515 IEA protein binding
GO:0005737 IEA cytoplasm
GO:0005886 TAS plasma membrane
GO:0007275 IEA multicellular organismal development
GO:0007411 TAS axon guidance
GO:0014911 IEA positive regulation of smooth muscle cell migration
GO:0014912 IEA negative regulation of smooth muscle cell migration
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0021591 IEA ventricular system development
GO:0030215 IEA semaphorin receptor binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000011533 sema6dl protein_coding Danio_rerio
ENSMUSG00000027200 Sema6d protein_coding Mus_musculus

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