ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: hypermethylated in cancer 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000177374 HIC1 9606 + 17:2054154-2063241 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000322941 HIC1-005 2056310-2059686 protein_coding
  ENST00000399849 HIC1-201 2055099-2059686 protein_coding
  ENST00000571875 HIC1-002 2054215-2056889 protein_coding
  ENST00000571990 HIC1-003 2054215-2056979 protein_coding
  ENST00000574370 HIC1-001 2054154-2056719 protein_coding
  ENST00000576444 HIC1-004 2056219-2056943 protein_coding
  ENST00000619757 HIC1-006 2055099-2063241 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000322941ENST00000399849ENST00000619757
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000322941 23.415±0.00 N/A N/A N/A
ENST00000399849 N/A 6.682±0.00 35.599±0.00 19.730±7.56
ENST00000619757 N/A N/A N/A 1.289±0.40

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00093G CIL_00093G_0001 VISTA
CIL_0007RP CIL_0007RP_0001 VISTA
CIL_0007KQ CIL_0007KQ_0001 UCNEbase

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA:ISS negative regulation of transcription from RNA polymerase II promoter
GO:0000785 ISS chromatin
GO:0003700 IEA:IDA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 TAS regulation of transcription, DNA-templated
GO:0007275 IEA multicellular organismal development
GO:0008630 IEA:IDA intrinsic apoptotic signaling pathway in response to DNA damage
GO:0016055 IEA Wnt signaling pathway
GO:0030178 IDA negative regulation of Wnt signaling pathway
GO:0042826 IDA histone deacetylase binding
GO:0043517 ISS positive regulation of DNA damage response, signal transduction by p53 class mediator
GO:0043565 IDA sequence-specific DNA binding
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000055493 hic1 protein_coding Danio_rerio
ENSMUSG00000043099 Hic1 protein_coding Mus_musculus

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