ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: SIVA1, apoptosis-inducing factor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000184990 SIVA1 9606 + 14:104753100-104768494 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000329967 SIVA1-001 104753100-104759657 protein_coding
  ENST00000347067 SIVA1-002 104753159-104759659 protein_coding
  ENST00000535554 SIVA1-004 104753147-104757479 retained_intron
  ENST00000553810 SIVA1-007 104753160-104757312 protein_coding
  ENST00000553819 SIVA1-008 104753171-104768494 nonsense_mediated_decay
  ENST00000554013 SIVA1-006 104753181-104756925 retained_intron
  ENST00000556195 SIVA1-005 104753718-104759578 protein_coding
  ENST00000556431 SIVA1-003 104753202-104759653 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000329967ENST00000347067ENST00000553810ENST00000556431
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000329967 62.202±7.93 42.930±18.09 52.237±0.00 26.126±0.00 52.035±50.84
ENST00000347067 132.340±32.28 62.064±20.13 55.036±0.00 19.423±0.00 14.434±9.15
ENST00000553810 106.609±22.50 25.343±11.38 N/A 13.104±0.00 30.111±26.30
ENST00000556431 N/A 1.479±0.53 N/A 1.916±0.00 1.978±2.18

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00059G CIL_00059G_0002 CGP
CIL_0001G0 CIL_0001G0_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001618 ISS virus receptor activity
GO:0005175 IPI CD27 receptor binding
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005654 IDA nucleoplasm
GO:0005737 IEA cytoplasm
GO:0005739 IDA mitochondrion
GO:0006924 IDA activation-induced cell death of T cells
GO:0008270 IDA zinc ion binding
GO:0009615 ISS response to virus
GO:0016032 IEA viral process
GO:0032088 IDA negative regulation of NF-kappaB transcription factor activity
GO:0046872 IEA metal ion binding
GO:0097191 IDA extrinsic apoptotic signaling pathway
GO:0097193 IDA intrinsic apoptotic signaling pathway
GO:1901030 IDA positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000059830 Gm16380 protein_coding Mus_musculus
ENSMUSG00000064326 Siva1 protein_coding Mus_musculus

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