ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000022623 Shank3 10090 + 15:89499623-89560261 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000039074 Shank3-201 89499857-89560261 protein_coding
  ENSMUST00000066545 Shank3-002 89501283-89560259 protein_coding
  ENSMUST00000109309 Shank3-001 89499623-89560261 protein_coding
  ENSMUST00000123799 Shank3-005 89530796-89532408 processed_transcript
  ENSMUST00000135214 Shank3-003 89500123-89503421 processed_transcript
  ENSMUST00000154240 Shank3-004 89524322-89534394 processed_transcript
  ENSMUST00000167173 Shank3-006 89532890-89543816 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000039074ENSMUST00000109309
Transcript ID C166 Tie2+ EC mES
ENSMUST00000039074 0.144±0.00 3.609±0.00 N/A
ENSMUST00000109309 0.212±0.03 N/A 4.111±0.35

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000165 IGI MAPK cascade
GO:0001838 IGI embryonic epithelial tube formation
GO:0003779 IEA actin binding
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0005886 IDA plasma membrane
GO:0007416 IMP synapse assembly
GO:0007612 IMP learning
GO:0007613 IMP memory
GO:0008022 IPI protein C-terminus binding
GO:0008270 ISS zinc ion binding
GO:0017124 ISS SH3 domain binding
GO:0021773 IMP striatal medium spiny neuron differentiation
GO:0030054 IEA cell junction
GO:0030160 ISS GKAP/Homer scaffold activity
GO:0032232 IDA negative regulation of actin filament bundle assembly
GO:0035176 IMP social behavior
GO:0035255 IPI ionotropic glutamate receptor binding
GO:0035641 IMP locomotory exploration behavior
GO:0042802 ISS identical protein binding
GO:0043005 IDA neuron projection
GO:0044309 IDA neuron spine
GO:0045211 IEA postsynaptic membrane
GO:0045794 IMP negative regulation of cell volume
GO:0048170 IMP positive regulation of long-term neuronal synaptic plasticity
GO:0048854 IMP brain morphogenesis
GO:0050885 IMP neuromuscular process controlling balance
GO:0051835 IMP positive regulation of synapse structural plasticity
GO:0051968 IMP positive regulation of synaptic transmission, glutamatergic
GO:0060076 IC excitatory synapse
GO:0060170 ISS ciliary membrane
GO:0060997 IMP dendritic spine morphogenesis
GO:0060999 IMP positive regulation of dendritic spine development
GO:0061001 IMP regulation of dendritic spine morphogenesis
GO:0071625 IMP vocalization behavior
GO:0097107 IMP postsynaptic density assembly
GO:0097110 IPI scaffold protein binding
GO:0097113 IMP alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering
GO:0097114 IMP N-methyl-D-aspartate receptor clustering
GO:0097117 IMP guanylate kinase-associated protein clustering
GO:0097481 ISS neuronal postsynaptic density
GO:1900271 IMP regulation of long-term synaptic potentiation
GO:1900451 IMP positive regulation of glutamate receptor signaling pathway
GO:1900452 IMP regulation of long term synaptic depression
GO:2000463 IMP positive regulation of excitatory postsynaptic membrane potential
GO:2000821 IMP regulation of grooming behavior
GO:2000822 IMP regulation of behavioral fear response
GO:2000969 IMP positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000063054 shank3b protein_coding Danio_rerio
ENSDARG00000063332 shank3a protein_coding Danio_rerio

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