ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000031987 Egln1 10090 - 8:124908596-124949254 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000034469 Egln1-201 124908596-124949254 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000034469
Transcript ID C166 Tie2+ EC mES
ENSMUST00000034469 20.544±2.27 16.568±4.74 57.165±4.83

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0007WK CIL_0007WK_0002 VISTA
CIL_0006AZ CIL_0006AZ_0002 CGP
CIL_0006AY CIL_0006AY_0002 CGP

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001666 IEA response to hypoxia
GO:0005506 IEA iron ion binding
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005829 IEA cytosol
GO:0018401 IEA peptidyl-proline hydroxylation to 4-hydroxy-L-proline
GO:0019899 IEA enzyme binding
GO:0030821 IEA negative regulation of cAMP catabolic process
GO:0031418 IEA L-ascorbic acid binding
GO:0031543 IEA peptidyl-proline dioxygenase activity
GO:0031545 IEA peptidyl-proline 4-dioxygenase activity
GO:0032364 IEA oxygen homeostasis
GO:0043433 IEA negative regulation of sequence-specific DNA binding transcription factor activity
GO:0045765 IMP regulation of angiogenesis
GO:0051344 IEA negative regulation of cyclic-nucleotide phosphodiesterase activity
GO:0055008 IMP cardiac muscle tissue morphogenesis
GO:0055114 IEA oxidation-reduction process
GO:0060347 IMP heart trabecula formation
GO:0060412 IMP ventricular septum morphogenesis
GO:0060711 IMP labyrinthine layer development
GO:0071731 ISS response to nitric oxide

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000004632 egln1b protein_coding Danio_rerio
ENSDARG00000038996 egln1a protein_coding Danio_rerio
ENSG00000135766 EGLN1 egl-9 family hypoxia-inducible factor 1 protein_coding Homo_sapiens

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