ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000032494 Tdgf1 10090 - 9:110939603-110946158 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000035075 Tdgf1-001 110939603-110946158 protein_coding
  ENSMUST00000197460 Tdgf1-004 110940243-110946094 nonsense_mediated_decay
  ENSMUST00000199196 Tdgf1-002 110942642-110944871 protein_coding
  ENSMUST00000199782 Tdgf1-003 110942357-110946075 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECENSMUST00000035075
Transcript ID C166 Tie2+ EC
ENSMUST00000035075 0.017±0.00 0.034±0.02

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000187 ISO activation of MAPK activity
GO:0001570 IMP vasculogenesis
GO:0001701 IMP in utero embryonic development
GO:0001954 IMP positive regulation of cell-matrix adhesion
GO:0002042 IEA cell migration involved in sprouting angiogenesis
GO:0005102 IEA receptor binding
GO:0005515 IPI protein binding
GO:0005615 IDA extracellular space
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005794 IDA Golgi apparatus
GO:0007369 IGI gastrulation
GO:0007507 IEA heart development
GO:0008083 ISO growth factor activity
GO:0008284 ISO positive regulation of cell proliferation
GO:0008595 IMP anterior/posterior axis specification, embryo
GO:0009948 IGI anterior/posterior axis specification
GO:0009966 IDA regulation of signal transduction
GO:0009986 IDA cell surface
GO:0010595 IEA positive regulation of endothelial cell migration
GO:0016324 IEA apical plasma membrane
GO:0018105 IEA peptidyl-serine phosphorylation
GO:0019897 IDA extrinsic component of plasma membrane
GO:0030334 IMP regulation of cell migration
GO:0030335 IEA positive regulation of cell migration
GO:0030509 IDA BMP signaling pathway
GO:0030512 IGI negative regulation of transforming growth factor beta receptor signaling pathway
GO:0035729 IEA cellular response to hepatocyte growth factor stimulus
GO:0043066 IEA negative regulation of apoptotic process
GO:0044344 IEA cellular response to fibroblast growth factor stimulus
GO:0045121 IEA membrane raft
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter
GO:0048146 IMP positive regulation of fibroblast proliferation
GO:0048471 IDA perinuclear region of cytoplasm
GO:0050731 IEA positive regulation of peptidyl-tyrosine phosphorylation
GO:0055007 IMP cardiac muscle cell differentiation
GO:0060070 IDA canonical Wnt signaling pathway
GO:0071346 IEA cellular response to interferon-gamma
GO:0071354 IEA cellular response to interleukin-6
GO:0071356 IEA cellular response to tumor necrosis factor
GO:0071364 IEA cellular response to epidermal growth factor stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000035095 tdgf1 protein_coding Danio_rerio
ENSG00000241186 TDGF1 teratocarcinoma-derived growth factor 1 protein_coding Homo_sapiens

Loading