ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000037936 Scarb1 10090 - 5:125277087-125341094 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000086075 Scarb1-001 125277087-125341094 protein_coding
  ENSMUST00000111390 Scarb1-002 125277089-125341071 protein_coding
  ENSMUST00000123338 Scarb1-009 125297319-125304542 retained_intron
  ENSMUST00000124582 Scarb1-010 125277787-125284159 processed_transcript
  ENSMUST00000127148 Scarb1-005 125277566-125294109 protein_coding
  ENSMUST00000133624 Scarb1-008 125300360-125316632 processed_transcript
  ENSMUST00000135736 Scarb1-004 125282950-125286677 retained_intron
  ENSMUST00000137783 Scarb1-006 125303189-125340008 protein_coding
  ENSMUST00000148373 Scarb1-003 125283355-125341019 retained_intron
  ENSMUST00000156532 Scarb1-007 125304249-125326267 processed_transcript
  ENSMUST00000197310 Scarb1-011 125325261-125327719 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000086075ENSMUST00000111390ENSMUST00000197310
Transcript ID C166 Tie2+ EC mES
ENSMUST00000086075 30.527±3.89 72.911±62.50 N/A
ENSMUST00000111390 5.985±0.85 29.758±17.15 36.831±16.80
ENSMUST00000197310 N/A 2.837±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_000399 CIL_000399_0002 CGP
CIL_00006N CIL_00006N_0003 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001530 IEA lipopolysaccharide binding
GO:0001875 IEA lipopolysaccharide receptor activity
GO:0001935 IMP endothelial cell proliferation
GO:0005515 IEA protein binding
GO:0005737 IEA cytoplasm
GO:0005765 IEA lysosomal membrane
GO:0005886 ISS plasma membrane
GO:0005887 IDA integral component of plasma membrane
GO:0005901 IDA caveola
GO:0006702 IEA androgen biosynthetic process
GO:0006707 IMP cholesterol catabolic process
GO:0006869 IEA lipid transport
GO:0006898 IEA receptor-mediated endocytosis
GO:0006910 IEA phagocytosis, recognition
GO:0007155 IEA cell adhesion
GO:0008035 IDA high-density lipoprotein particle binding
GO:0009986 IEA cell surface
GO:0010867 IMP positive regulation of triglyceride biosynthetic process
GO:0010886 ISS positive regulation of cholesterol storage
GO:0010899 IMP regulation of phosphatidylcholine catabolic process
GO:0015914 IMP phospholipid transport
GO:0015920 IEA lipopolysaccharide transport
GO:0016021 IDA integral component of membrane
GO:0030169 ISS low-density lipoprotein particle binding
GO:0030301 IMP cholesterol transport
GO:0031528 IEA microvillus membrane
GO:0031663 IEA lipopolysaccharide-mediated signaling pathway
GO:0032497 IEA detection of lipopolysaccharide
GO:0033344 IDA cholesterol efflux
GO:0034185 IPI apolipoprotein binding
GO:0034186 IEA apolipoprotein A-I binding
GO:0034375 IMP high-density lipoprotein particle remodeling
GO:0034383 IMP low-density lipoprotein particle clearance
GO:0034384 ISS high-density lipoprotein particle clearance
GO:0042632 IMP cholesterol homeostasis
GO:0042803 IEA protein homodimerization activity
GO:0043534 IMP blood vessel endothelial cell migration
GO:0043654 ISS recognition of apoptotic cell
GO:0043691 IMP reverse cholesterol transport
GO:0044406 IEA adhesion of symbiont to host
GO:0051000 IEA positive regulation of nitric-oxide synthase activity
GO:0070062 IEA extracellular vesicular exosome
GO:0070328 IMP triglyceride homeostasis
GO:0070506 ISS high-density lipoprotein particle receptor activity
GO:0070508 IDA cholesterol import

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000073060 SCARB1 scavenger receptor class B, member 1 protein_coding Homo_sapiens

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