ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: heparanase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000311412 HPSE-002 ENSG00000173083 9606 - 4:83292461-83334882 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000311412
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000311412 0.390±0.00 8.417±4.43 7.232±0.00 1.336±0.93

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004566 TAS beta-glucuronidase activity
GO:0005515 IPI protein binding
GO:0005576 IEA extracellular region
GO:0005634 IDA nucleus
GO:0005764 IDA lysosome
GO:0005975 TAS carbohydrate metabolic process
GO:0006027 TAS glycosaminoglycan catabolic process
GO:0006029 TAS proteoglycan metabolic process
GO:0007160 IDA cell-matrix adhesion
GO:0010575 IDA positive regulation vascular endothelial growth factor production
GO:0016020 IEA membrane
GO:0016798 IEA hydrolase activity, acting on glycosyl bonds
GO:0030194 IDA positive regulation of blood coagulation
GO:0030200 IDA heparan sulfate proteoglycan catabolic process
GO:0030203 TAS glycosaminoglycan metabolic process
GO:0030305 IDA heparanase activity
GO:0033690 IDA positive regulation of osteoblast proliferation
GO:0043202 TAS lysosomal lumen
GO:0043231 IDA intracellular membrane-bounded organelle
GO:0044281 TAS small molecule metabolic process
GO:0045545 IDA syndecan binding
GO:0046983 IDA protein dimerization activity
GO:0051797 IDA regulation of hair follicle development
GO:0051897 IDA positive regulation of protein kinase B signaling

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000045617 Hpse-001 protein_coding Mus_musculus 0 1247
ENSMUST00000112908 Hpse-002 protein_coding Mus_musculus 0 1098
ENSMUST00000145380 Ckmt1-003 retained_intron Mus_musculus 0.000006 58

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