ANGIOGENES

ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info
Description:	cytochrome P450, family 51, subfamily A, polypeptide 1
Gene Accession	Gene Name	Tax ID	Strand	Position	Gene Biotype
ENSG00000001630	CYP51A1	9606	-	7:92112151-92142952	protein_coding
	Transcript Accession		Transcript Name	Position	Transcript Biotype
	ENST00000003100		CYP51A1-001	92112151-92134530	protein_coding
	ENST00000422867		CYP51A1-006	92113585-92123844	protein_coding
	ENST00000435873		CYP51A1-005	92131807-92142952	protein_coding
	ENST00000450723		CYP51A1-002	92113412-92134803	protein_coding
	ENST00000482924		CYP51A1-003	92113694-92117448	retained_intron

Expression Patterns

Transcript ID	BECs	HAoEC	HMVEC-D	HUVEC
ENST00000003100	4.549±0.00	11.672±8.88	21.741±0.00	24.628±23.02
ENST00000450723	N/A	11.539±0.69	N/A	N/A

Conserved Regions
Region ID	Sub-Region	Region Type
CIL_0006E3	CIL_0006E3_0001	CGP

Gene Ontology
GO ID	Evidence Type	GO Description
GO:0005506	IEA	iron ion binding
GO:0005783	IDA	endoplasmic reticulum
GO:0005789	TAS	endoplasmic reticulum membrane
GO:0006694	IDA	steroid biosynthetic process
GO:0006695	TAS	cholesterol biosynthetic process
GO:0006805	TAS	xenobiotic metabolic process
GO:0008398	IDA	sterol 14-demethylase activity
GO:0016020	IDA	membrane
GO:0016021	IEA	integral component of membrane
GO:0016125	TAS	sterol metabolic process
GO:0016705	IEA	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0020037	IDA:IEA	heme binding
GO:0033488	IEA	cholesterol biosynthetic process via 24,25-dihydrolanosterol
GO:0043231	IEA	intracellular membrane-bounded organelle
GO:0044281	TAS	small molecule metabolic process
GO:0055114	IEA	oxidation-reduction process
GO:0070988	IEA	demethylation

Homologs
ENSEMBL Accession	Gene Name	Description	Biotype	Species
ENSDARG00000042641	cyp51		protein_coding	Danio_rerio
ENSMUSG00000001467	Cyp51		protein_coding	Mus_musculus

Loading