ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: mannose-6-phosphate receptor (cation dependent)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000003056 M6PR 9606 - 12:8940363-8949955 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000000412 M6PR-001 8940365-8949955 protein_coding
  ENST00000536844 M6PR-201 8940364-8949761 protein_coding
  ENST00000537621 M6PR-009 8942179-8943886 protein_coding
  ENST00000539143 M6PR-010 8940363-8943420 protein_coding
  ENST00000540837 M6PR-006 8945237-8949610 retained_intron
  ENST00000541507 M6PR-002 8940363-8949636 nonsense_mediated_decay
  ENST00000543159 M6PR-005 8945485-8946848 protein_coding
  ENST00000543258 M6PR-007 8942451-8946240 nonsense_mediated_decay
  ENST00000543704 M6PR-011 8941649-8946368 protein_coding
  ENST00000543834 M6PR-008 8943296-8945479 retained_intron
  ENST00000543845 M6PR-004 8945433-8949645 protein_coding
  ENST00000544193 M6PR-012 8940751-8942517 protein_coding
  ENST00000544245 M6PR-003 8943825-8949735 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000000412ENST00000536844ENST00000539143ENST00000541507ENST00000543704
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000000412 N/A 16.492±1.00 N/A N/A 21.145±10.90
ENST00000536844 N/A 14.192±2.29 N/A 23.685±0.00 14.416±5.86
ENST00000539143 54.889±2.03 N/A 85.346±0.00 N/A N/A
ENST00000541507 18.657±4.83 37.640±9.49 22.860±0.00 22.361±0.00 29.521±13.01
ENST00000543704 N/A 48.200±0.01 N/A 50.581±0.00 24.894±16.61

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0008HL CIL_0008HL_0001 VISTA

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000323 IEA lytic vacuole
GO:0004888 TAS transmembrane signaling receptor activity
GO:0005537 IEA mannose binding
GO:0005764 IEA lysosome
GO:0005768 IDA endosome
GO:0005770 IEA late endosome
GO:0005887 TAS integral component of plasma membrane
GO:0006898 TAS receptor-mediated endocytosis
GO:0007165 TAS signal transduction
GO:0008333 TAS endosome to lysosome transport
GO:0015578 IEA mannose transmembrane transporter activity
GO:0015761 IEA mannose transport
GO:0016020 IDA membrane
GO:0016021 IEA integral component of membrane

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000018432 m6pr protein_coding Danio_rerio
ENSMUSG00000007458 M6pr protein_coding Mus_musculus

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