ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: caspase 10, apoptosis-related cysteine peptidase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000003400 CASP10 9606 + 2:201182881-201229406 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000272879 CASP10-002 201183132-201229406 protein_coding
  ENST00000286186 CASP10-001 201182881-201221665 protein_coding
  ENST00000313728 CASP10-009 201183192-201217770 protein_coding
  ENST00000346817 CASP10-003 201183169-201220080 protein_coding
  ENST00000360132 CASP10-201 201182898-201221660 protein_coding
  ENST00000374650 CASP10-007 201183160-201200728 protein_coding
  ENST00000438843 CASP10-006 201183141-201208160 nonsense_mediated_decay
  ENST00000448480 CASP10-010 201183195-201229128 protein_coding
  ENST00000460140 CASP10-005 201183112-201206250 retained_intron
  ENST00000471191 CASP10-012 201187680-201196015 retained_intron
  ENST00000484926 CASP10-011 201183216-201186380 retained_intron
  ENST00000485408 CASP10-013 201187746-201193403 retained_intron
  ENST00000492363 CASP10-004 201185778-201217741 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000286186ENST00000346817ENST00000360132
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000286186 1.001±0.00 2.102±0.46 N/A 2.584±1.23
ENST00000346817 2.229±0.26 3.651±0.86 7.697±0.00 5.960±2.40
ENST00000360132 2.683±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00089O CIL_00089O_0001 VISTA

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004197 TAS:IEA cysteine-type endopeptidase activity
GO:0005515 IPI:IEA protein binding
GO:0005737 IBA cytoplasm
GO:0005829 TAS cytosol
GO:0005886 TAS plasma membrane
GO:0006508 IEA proteolysis
GO:0006915 IBA:IEA apoptotic process
GO:0008234 IEA cysteine-type peptidase activity
GO:0031265 IDA CD95 death-inducing signaling complex
GO:0031625 IPI ubiquitin protein ligase binding
GO:0035877 IPI death effector domain binding
GO:0042981 IEA regulation of apoptotic process
GO:0043123 IMP positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045087 TAS innate immune response
GO:0097190 TAS apoptotic signaling pathway
GO:0097199 IMP cysteine-type endopeptidase activity involved in apoptotic signaling pathway
GO:0097342 IDA ripoptosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000070272 casp8l2 protein_coding Danio_rerio

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