ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000003989 SLC7A2 9606 + 8:17497088-17570573 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000004531 SLC7A2-201 17538777-17570561 protein_coding
  ENST00000398090 SLC7A2-202 17538777-17570561 protein_coding
  ENST00000470360 SLC7A2-002 17497215-17570573 protein_coding
  ENST00000494857 SLC7A2-001 17497088-17570573 protein_coding
  ENST00000522656 SLC7A2-003 17497091-17565274 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000004531ENST00000398090ENST00000494857ENST00000522656
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000004531 2.071±1.37 1.022±0.27 N/A N/A 0.917±0.78
ENST00000398090 N/A N/A N/A N/A 0.178±0.00
ENST00000494857 0.459±0.00 5.245±2.81 0.728±0.00 20.899±0.00 3.162±2.70
ENST00000522656 N/A N/A N/A N/A 3.826±4.38

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0001TT CIL_0001TT_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000064 IEA L-ornithine transmembrane transporter activity
GO:0002537 IEA nitric oxide production involved in inflammatory response
GO:0003333 IEA amino acid transmembrane transport
GO:0005289 IEA high-affinity arginine transmembrane transporter activity
GO:0005292 IEA high-affinity lysine transmembrane transporter activity
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006520 TAS cellular amino acid metabolic process
GO:0006809 IEA nitric oxide biosynthetic process
GO:0006810 TAS:IEA transport
GO:0006811 TAS ion transport
GO:0006865 TAS:IEA amino acid transport
GO:0015171 IEA amino acid transmembrane transporter activity
GO:0015174 TAS basic amino acid transmembrane transporter activity
GO:0015181 IEA arginine transmembrane transporter activity
GO:0015189 IEA L-lysine transmembrane transporter activity
GO:0016020 TAS:IEA membrane
GO:0016021 IEA integral component of membrane
GO:0042116 IEA macrophage activation
GO:0043030 IEA regulation of macrophage activation
GO:0050727 IEA regulation of inflammatory response
GO:0055085 TAS:IEA transmembrane transport
GO:0061459 IEA L-arginine transmembrane transporter activity
GO:0097626 IEA low-affinity L-arginine transmembrane transporter activity
GO:0097627 IEA high-affinity L-ornithine transmembrane transporter activity
GO:0097638 IEA L-arginine import across plasma membrane
GO:0097639 IEA L-lysine import across plasma membrane
GO:0097640 IEA L-ornithine import across plasma membrane
GO:1902023 IEA L-arginine transport
GO:1903352 IEA L-ornithine transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000037097 slc7a2 protein_coding Danio_rerio
ENSMUSG00000031596 Slc7a2 protein_coding Mus_musculus

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