ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: v-ral simian leukemia viral oncogene homolog A (ras related)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000006451 RALA 9606 + 7:39623483-39708124 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000005257 RALA-001 39623483-39708124 protein_coding
  ENST00000434466 RALA-002 39686687-39706308 nonsense_mediated_decay
  ENST00000436179 RALA-003 39623886-39690570 protein_coding
  ENST00000466491 RALA-005 39700880-39706302 processed_transcript
  ENST00000468201 RALA-004 39623565-39706391 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000005257ENST00000434466
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000005257 49.752±16.98 53.553±32.83 20.198±0.00 77.634±0.00 104.256±59.56
ENST00000434466 26.868±0.00 46.166±25.66 N/A N/A 109.863±7.33

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000910 IDA cytokinesis
GO:0003924 IEA GTPase activity
GO:0005515 IPI protein binding
GO:0005525 IEA GTP binding
GO:0005622 IEA intracellular
GO:0005886 IEA:IDA plasma membrane
GO:0005925 IDA focal adhesion
GO:0006184 IEA GTP catabolic process
GO:0006886 IEA intracellular protein transport
GO:0006887 IEA exocytosis
GO:0006913 IEA nucleocytoplasmic transport
GO:0006935 TAS chemotaxis
GO:0007165 TAS:IEA signal transduction
GO:0007264 IEA small GTPase mediated signal transduction
GO:0007265 IEA:TAS Ras protein signal transduction
GO:0009986 IDA cell surface
GO:0015031 IEA protein transport
GO:0016020 IEA membrane
GO:0016032 IEA viral process
GO:0017157 IDA regulation of exocytosis
GO:0030139 IDA endocytic vesicle
GO:0030659 TAS cytoplasmic vesicle membrane
GO:0031532 IDA actin cytoskeleton reorganization
GO:0031755 IDA Edg-2 lysophosphatidic acid receptor binding
GO:0032154 IDA cleavage furrow
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0051491 IDA positive regulation of filopodium assembly
GO:0051665 IDA membrane raft localization
GO:0061024 TAS membrane organization
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000016253 ralab protein_coding Danio_rerio
ENSDARG00000045463 ralaa protein_coding Danio_rerio
ENSMUSG00000008859 Rala protein_coding Mus_musculus

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