ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: lysine (K)-specific demethylase 7A
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000006459 KDM7A 9606 - 7:140084746-140177035 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000397560 KDM7A-001 140084746-140177035 protein_coding
  ENST00000472616 KDM7A-002 140084855-140119142 nonsense_mediated_decay
  ENST00000478996 KDM7A-003 140090903-140092141 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000397560ENST00000472616
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000397560 0.054±0.00 0.669±0.35 N/A 1.629±0.00 1.123±0.75
ENST00000472616 0.150±0.00 0.178±0.10 0.354±0.00 N/A 0.504±0.13

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0008ZU CIL_0008ZU_0001 VISTA
CIL_00030A CIL_00030A_0001 CGP
CIL_000307 CIL_000307_0001 CGP

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005506 IDA iron ion binding
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0005730 IDA nucleolus
GO:0006351 IEA transcription, DNA-templated
GO:0008270 IDA:IEA zinc ion binding
GO:0016706 IDA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0030901 ISS midbrain development
GO:0032454 IDA histone demethylase activity (H3-K9 specific)
GO:0033169 IDA histone H3-K9 demethylation
GO:0035064 IDA methylated histone binding
GO:0035574 IDA histone H4-K20 demethylation
GO:0035575 IDA histone demethylase activity (H4-K20 specific)
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0051864 IDA histone demethylase activity (H3-K36 specific)
GO:0055114 IEA oxidation-reduction process
GO:0070544 IDA histone H3-K36 demethylation
GO:0071557 IDA histone H3-K27 demethylation
GO:0071558 IDA histone demethylase activity (H3-K27 specific)

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000018111 kdm7aa protein_coding Danio_rerio
ENSDARG00000018559 kdm7ab protein_coding Danio_rerio
ENSMUSG00000042599 Kdm7a protein_coding Mus_musculus

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