ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: thromboxane A2 receptor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000006638 TBXA2R 9606 - 19:3594506-3606840 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000375190 TBXA2R-001 3594506-3606840 protein_coding
  ENST00000411851 TBXA2R-003 3594780-3606660 protein_coding
  ENST00000587717 TBXA2R-002 3597922-3600133 processed_transcript
  ENST00000589966 TBXA2R-004 3594552-3600669 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000375190ENST00000411851ENST00000587717ENST00000589966
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000375190 0.564±0.00 0.705±0.44 6.009±0.00 N/A 1.436±1.28
ENST00000411851 2.040±1.16 1.488±0.83 N/A 2.128±0.00 1.618±1.26
ENST00000587717 N/A 1.048±0.00 N/A N/A N/A
ENST00000589966 1.536±0.16 0.610±0.27 27.493±0.00 N/A 0.996±0.90

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001669 IEA acrosomal vesicle
GO:0004930 IEA G-protein coupled receptor activity
GO:0004960 IEA thromboxane receptor activity
GO:0004961 TAS thromboxane A2 receptor activity
GO:0005085 TAS guanyl-nucleotide exchange factor activity
GO:0005515 IPI protein binding
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006954 IEA inflammatory response
GO:0007186 TAS:IEA G-protein coupled receptor signaling pathway
GO:0007204 IEA positive regulation of cytosolic calcium ion concentration
GO:0007584 IEA response to nutrient
GO:0007596 TAS blood coagulation
GO:0016021 IEA integral component of membrane
GO:0019229 IEA regulation of vasoconstriction
GO:0019932 IEA second-messenger-mediated signaling
GO:0030168 TAS platelet activation
GO:0032496 IEA response to lipopolysaccharide
GO:0038193 TAS thromboxane A2 signaling pathway
GO:0042493 IEA response to drug
GO:0043547 TAS positive regulation of GTPase activity
GO:0045766 IEA positive regulation of angiogenesis
GO:0045777 IEA positive regulation of blood pressure
GO:0045907 IEA positive regulation of vasoconstriction
GO:0045987 IEA positive regulation of smooth muscle contraction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000034881 Tbxa2r protein_coding Mus_musculus

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