ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: MAP/microtubule affinity-regulating kinase 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000007047 MARK4 9606 + 19:45079288-45305283 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000262891 MARK4-001 45251258-45303693 protein_coding
  ENST00000300843 MARK4-002 45251292-45305283 protein_coding
  ENST00000587566 MARK4-010 45079288-45266246 protein_coding
  ENST00000588533 MARK4-007 45262991-45271677 retained_intron
  ENST00000588621 MARK4-003 45264687-45288552 retained_intron
  ENST00000590897 MARK4-009 45280145-45287664 retained_intron
  ENST00000590909 MARK4-006 45258893-45266281 protein_coding
  ENST00000592207 MARK4-008 45271476-45287664 nonsense_mediated_decay
  ENST00000592762 MARK4-005 45251387-45280657 nonsense_mediated_decay
  ENST00000620044 MARK4-201 45251387-45303681 protein_coding
  ENST00000622871 MARK4-202 45294355-45303369 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000262891ENST00000300843ENST00000620044
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000262891 11.397±0.00 19.952±13.30 5.489±0.00 8.950±0.00 14.229±10.94
ENST00000300843 N/A N/A N/A N/A 0.399±0.18
ENST00000620044 10.409±0.00 N/A 14.804±0.00 N/A N/A

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000226 IMP microtubule cytoskeleton organization
GO:0001578 IEP microtubule bundle formation
GO:0004672 IEA protein kinase activity
GO:0004674 IDA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA:NAS ATP binding
GO:0005813 IDA centrosome
GO:0005815 IDA microtubule organizing center
GO:0006468 IEA:TAS protein phosphorylation
GO:0007399 IDA nervous system development
GO:0008017 IDA microtubule binding
GO:0015630 IDA microtubule cytoskeleton
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0043005 IDA neuron projection
GO:0043015 IDA gamma-tubulin binding
GO:0043068 NAS positive regulation of programmed cell death
GO:0043130 NAS ubiquitin binding
GO:0050321 IDA tau-protein kinase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000023914 mark4a protein_coding Danio_rerio
ENSDARG00000024966 MARK4 (2 of 2) protein_coding Danio_rerio
ENSMUSG00000030397 Mark4 protein_coding Mus_musculus

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