ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: membrane-bound transcription factor peptidase, site 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000012174 MBTPS2 9606 + X:21839636-21885424 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000365779 MBTPS2-002 21839654-21873084 protein_coding
  ENST00000379484 MBTPS2-001 21839636-21885424 protein_coding
  ENST00000465888 MBTPS2-003 21839636-21857593 processed_transcript

Homo sapiens Ensembl GRCh38

Genome
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Sequences
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Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000365779ENST00000379484ENST00000465888
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000365779 N/A N/A N/A N/A 0.358±0.02
ENST00000379484 0.729±0.39 5.773±1.41 1.391±0.00 10.143±0.00 5.218±3.20
ENST00000465888 N/A N/A N/A N/A 1.156±0.78

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0002L6 CIL_0002L6_0002 CGP
CIL_0005Z6 CIL_0005Z6_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000139 TAS Golgi membrane
GO:0004222 IEA metalloendopeptidase activity
GO:0005515 IEA protein binding
GO:0005737 IDA cytoplasm
GO:0006508 IEA proteolysis
GO:0006987 TAS activation of signaling protein activity involved in unfolded protein response
GO:0008203 IEA cholesterol metabolic process
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0030968 TAS endoplasmic reticulum unfolded protein response
GO:0044267 TAS cellular protein metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000057577 mbtps2 protein_coding Danio_rerio
ENSMUSG00000046873 Mbtps2 protein_coding Mus_musculus

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