ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: proteasome (prosome, macropain) 26S subunit, ATPase, 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000013275 PSMC4 9606 + 19:39971005-39981441 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000157812 PSMC4-001 39971005-39981441 protein_coding
  ENST00000455878 PSMC4-002 39971170-39981441 protein_coding
  ENST00000593455 PSMC4-003 39971170-39981408 retained_intron
  ENST00000596386 PSMC4-006 39971192-39980061 retained_intron
  ENST00000601194 PSMC4-005 39979444-39980178 retained_intron
  ENST00000601697 PSMC4-004 39971180-39981441 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000157812ENST00000455878ENST00000593455ENST00000596386ENST00000601697
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000157812 16.340±0.00 12.277±2.68 N/A N/A 35.281±24.48
ENST00000455878 94.962±1.45 62.363±9.13 43.240±0.00 34.663±0.00 19.854±10.67
ENST00000593455 N/A N/A 11.129±0.00 5.494±0.00 7.041±5.65
ENST00000596386 N/A 24.249±4.30 N/A 15.551±0.00 13.123±7.06
ENST00000601697 N/A N/A 7.899±0.00 N/A 2.805±2.72

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000082 TAS G1/S transition of mitotic cell cycle
GO:0000209 TAS protein polyubiquitination
GO:0000278 TAS mitotic cell cycle
GO:0000502 IDA proteasome complex
GO:0001824 IEA blastocyst development
GO:0002474 TAS antigen processing and presentation of peptide antigen via MHC class I
GO:0002479 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA:IEA cytoplasm
GO:0005829 TAS cytosol
GO:0006200 TAS ATP catabolic process
GO:0006281 IEA DNA repair
GO:0006310 IEA DNA recombination
GO:0006508 TAS proteolysis
GO:0006521 TAS regulation of cellular amino acid metabolic process
GO:0006915 TAS apoptotic process
GO:0006977 TAS DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0009378 IEA four-way junction helicase activity
GO:0010467 TAS gene expression
GO:0016020 IDA membrane
GO:0016032 TAS viral process
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0016234 IEA inclusion body
GO:0016787 IEA hydrolase activity
GO:0016887 TAS:IEA ATPase activity
GO:0022624 ISS proteasome accessory complex
GO:0030163 IEA protein catabolic process
GO:0031145 TAS anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0031597 IEA cytosolic proteasome complex
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0042590 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0042981 TAS regulation of apoptotic process
GO:0043066 TAS negative regulation of apoptotic process
GO:0044281 TAS small molecule metabolic process
GO:0051436 TAS negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051437 TAS positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051439 TAS regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000027099 psmc4 protein_coding Danio_rerio
ENSMUSG00000030603 Psmc4 protein_coding Mus_musculus

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