ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: polymerase (DNA directed), alpha 2, accessory subunit
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000014138 POLA2 9606 + 11:65261762-65305589 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000265465 POLA2-001 65261762-65298685 protein_coding
  ENST00000525924 POLA2-008 65282507-65305589 protein_coding
  ENST00000527618 POLA2-004 65280468-65297616 retained_intron
  ENST00000527850 POLA2-003 65261920-65296498 nonsense_mediated_decay
  ENST00000532391 POLA2-005 65266481-65278826 protein_coding
  ENST00000532469 POLA2-002 65261932-65280020 retained_intron
  ENST00000533192 POLA2-006 65287602-65294776 retained_intron
  ENST00000534785 POLA2-007 65294178-65297552 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000265465ENST00000525924ENST00000527618ENST00000527850ENST00000532469ENST00000534785
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000265465 2.306±0.00 1.595±0.40 N/A N/A 1.471±0.85
ENST00000525924 6.018±0.00 N/A N/A N/A N/A
ENST00000527618 N/A 1.331±0.24 N/A N/A 4.183±3.73
ENST00000527850 N/A 1.444±0.24 N/A N/A 1.338±0.83
ENST00000532469 N/A N/A N/A N/A 1.637±1.02
ENST00000534785 34.278±9.62 10.254±2.11 10.858±0.00 5.148±0.00 3.968±1.65

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0008W1 CIL_0008W1_0001 VISTA

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000060 IEA protein import into nucleus, translocation
GO:0000082 TAS G1/S transition of mitotic cell cycle
GO:0000278 TAS mitotic cell cycle
GO:0000722 TAS telomere maintenance via recombination
GO:0000723 TAS telomere maintenance
GO:0003674 ND molecular_function
GO:0003677 IEA DNA binding
GO:0003887 IEA DNA-directed DNA polymerase activity
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005658 IBA alpha DNA polymerase:primase complex
GO:0005737 IDA cytoplasm
GO:0006260 NAS:IEA DNA replication
GO:0006270 IBA DNA replication initiation
GO:0006271 TAS DNA strand elongation involved in DNA replication
GO:0032201 TAS telomere maintenance via semi-conservative replication
GO:0046982 IBA protein heterodimerization activity
GO:0071897 IEA DNA biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015070 pola2 protein_coding Danio_rerio
ENSMUSG00000024833 Pola2 protein_coding Mus_musculus

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