ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: BH3 interacting domain death agonist
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000015475 BID 9606 - 22:17734138-17774770 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000317361 BID-002 17734138-17774016 protein_coding
  ENST00000342111 BID-003 17735499-17774412 protein_coding
  ENST00000399765 BID-004 17734175-17774489 protein_coding
  ENST00000399767 BID-201 17734142-17774495 protein_coding
  ENST00000399774 BID-001 17734171-17774492 protein_coding
  ENST00000473439 BID-006 17738058-17774495 processed_transcript
  ENST00000494097 BID-005 17735222-17741194 retained_intron
  ENST00000550946 BID-011 17735552-17774412 retained_intron
  ENST00000551952 BID-009 17735552-17774665 protein_coding
  ENST00000552886 BID-008 17739448-17774770 processed_transcript
  ENST00000611040 BID-202 17735552-17774665 protein_coding
  ENST00000614949 BID-203 17734142-17774495 protein_coding
  ENST00000615414 BID-204 17734142-17774042 protein_coding
  ENST00000617586 BID-205 17740031-17774495 protein_coding
  ENST00000622694 BID-206 17734142-17774495 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000342111ENST00000399765ENST00000399767ENST00000399774ENST00000473439ENST00000494097ENST00000551952ENST00000611040ENST00000614949ENST00000617586ENST00000622694
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000342111 10.419±0.00 N/A N/A N/A
ENST00000399765 10.277±3.33 4.494±2.36 6.744±0.00 3.872±1.51
ENST00000399767 N/A 3.065±0.03 N/A 4.480±2.51
ENST00000399774 3.518±0.00 3.072±1.14 N/A 4.950±2.22
ENST00000473439 N/A 8.622±0.00 N/A 13.230±1.38
ENST00000494097 N/A N/A N/A 1.004±0.01
ENST00000551952 32.590±0.00 13.195±5.75 31.583±0.00 17.221±7.11
ENST00000611040 66.636±1.88 26.114±10.94 N/A 40.645±21.81
ENST00000614949 N/A 2.246±0.79 N/A 2.178±0.00
ENST00000617586 N/A 6.293±0.00 N/A 20.903±1.45
ENST00000622694 12.334±0.00 4.944±3.63 9.457±0.00 4.397±2.43

Conserved Regions

Region IDSub-RegionRegion Type
CIL_000242 CIL_000242_0001 CGP
CIL_0002Z7 CIL_0002Z7_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001836 IDA release of cytochrome c from mitochondria
GO:0005123 TAS death receptor binding
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0005739 TAS mitochondrion
GO:0005741 TAS mitochondrial outer membrane
GO:0005829 TAS cytosol
GO:0006626 IEA protein targeting to mitochondrion
GO:0006915 TAS apoptotic process
GO:0006919 IEA activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007420 IEA brain development
GO:0008625 TAS extrinsic apoptotic signaling pathway via death domain receptors
GO:0008637 TAS apoptotic mitochondrial changes
GO:0016020 TAS membrane
GO:0031625 IEA ubiquitin protein ligase binding
GO:0032355 IEA response to estradiol
GO:0032459 IEA regulation of protein oligomerization
GO:0032461 IDA positive regulation of protein oligomerization
GO:0032464 IDA positive regulation of protein homooligomerization
GO:0032592 IEA integral component of mitochondrial membrane
GO:0034349 IEA glial cell apoptotic process
GO:0042127 IEA regulation of cell proliferation
GO:0042770 TAS signal transduction in response to DNA damage
GO:0043065 IMP:IEA positive regulation of apoptotic process
GO:0051260 IEA protein homooligomerization
GO:0051402 TAS neuron apoptotic process
GO:0070062 IDA extracellular vesicular exosome
GO:0090150 IDA establishment of protein localization to membrane
GO:0090200 IMP positive regulation of release of cytochrome c from mitochondria
GO:0097191 IEA extrinsic apoptotic signaling pathway
GO:0097193 TAS intrinsic apoptotic signaling pathway
GO:0097284 IEA hepatocyte apoptotic process
GO:0097345 IEA mitochondrial outer membrane permeabilization
GO:1900740 TAS positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
GO:1901030 TAS positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
GO:1902108 IEA regulation of mitochondrial membrane permeability involved in apoptotic process
GO:2000045 IEA regulation of G1/S transition of mitotic cell cycle
GO:2001238 IMP positive regulation of extrinsic apoptotic signaling pathway
GO:2001244 TAS positive regulation of intrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000004446 Bid protein_coding Mus_musculus

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