ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: GRB2-associated binding protein 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000033327 GAB2 9606 - 11:78215297-78418348 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000340149 GAB2-002 78215297-78341880 protein_coding
  ENST00000361507 GAB2-001 78215297-78417806 protein_coding
  ENST00000526030 GAB2-004 78226957-78417822 processed_transcript
  ENST00000528329 GAB2-007 78226620-78231932 processed_transcript
  ENST00000528886 GAB2-003 78250271-78418348 protein_coding
  ENST00000530915 GAB2-005 78250357-78417779 protein_coding
  ENST00000534823 GAB2-006 78280460-78417771 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; HAoECHMVEC-DHUVECENST00000340149ENST00000361507ENST00000528329
Transcript ID HAoEC HMVEC-D HUVEC
ENST00000340149 N/A N/A 2.384±1.91
ENST00000361507 4.288±2.59 5.455±0.00 6.759±3.22
ENST00000528329 N/A N/A 0.118±0.00

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005068 IDA transmembrane receptor protein tyrosine kinase adaptor activity
GO:0005515 IPI protein binding
GO:0005547 ISS phosphatidylinositol-3,4,5-trisphosphate binding
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005886 IDA plasma membrane
GO:0007169 IDA transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007229 IEA integrin-mediated signaling pathway
GO:0008284 IDA positive regulation of cell proliferation
GO:0016477 IEA cell migration
GO:0030316 IMP osteoclast differentiation
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0043306 ISS positive regulation of mast cell degranulation
GO:0043325 ISS phosphatidylinositol-3,4-bisphosphate binding
GO:0045087 TAS innate immune response
GO:0048015 ISS phosphatidylinositol-mediated signaling

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000004508 Gab2 protein_coding Mus_musculus

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