ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: death-associated protein kinase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000035664 DAPK2 9606 - 15:63907036-64072033 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000261891 DAPK2-201 63907036-64040267 protein_coding
  ENST00000457488 DAPK2-001 63907923-64046322 protein_coding
  ENST00000557867 DAPK2-010 63911852-63926201 retained_intron
  ENST00000558064 DAPK2-004 63909184-63911943 nonsense_mediated_decay
  ENST00000558069 DAPK2-202 63922735-64040267 protein_coding
  ENST00000558076 DAPK2-009 63924512-63926074 retained_intron
  ENST00000558482 DAPK2-008 63929551-64046436 processed_transcript
  ENST00000559007 DAPK2-002 63907036-64040267 nonsense_mediated_decay
  ENST00000559306 DAPK2-007 63983605-64072033 protein_coding
  ENST00000559731 DAPK2-011 63908253-63916592 processed_transcript
  ENST00000559897 DAPK2-006 63939293-64030020 processed_transcript
  ENST00000561162 DAPK2-005 63971524-64046381 nonsense_mediated_decay
  ENST00000612884 DAPK2-003 63916147-64046322 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000261891ENST00000457488ENST00000558064ENST00000558069ENST00000558482ENST00000559007ENST00000559731ENST00000559897ENST00000612884
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000261891 N/A 0.485±0.28 N/A 0.477±0.00 0.629±0.75
ENST00000457488 1.317±0.00 0.961±0.61 3.506±0.00 N/A 0.709±0.51
ENST00000558064 N/A N/A N/A N/A 0.766±0.00
ENST00000558069 N/A N/A N/A N/A 0.343±0.00
ENST00000558482 N/A N/A N/A N/A 0.591±0.45
ENST00000559007 0.227±0.00 0.117±0.06 N/A 0.222±0.00 0.243±0.34
ENST00000559731 1.909±0.00 N/A N/A N/A 0.139±0.00
ENST00000559897 N/A 0.223±0.00 N/A N/A N/A
ENST00000612884 0.146±0.00 0.043±0.01 N/A N/A 0.102±0.04

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00050A CIL_00050A_0002 CGP

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003824 IEA catalytic activity
GO:0004672 IEA protein kinase activity
GO:0004674 TAS protein serine/threonine kinase activity
GO:0004683 IBA calmodulin-dependent protein kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005516 IDA calmodulin binding
GO:0005524 IEA:IDA ATP binding
GO:0005737 IDA cytoplasm
GO:0006468 IEA:IDA protein phosphorylation
GO:0006915 TAS apoptotic process
GO:0010506 TAS regulation of autophagy
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0031410 IEA cytoplasmic vesicle
GO:0035556 IDA intracellular signal transduction
GO:0042802 IPI identical protein binding
GO:0042981 TAS regulation of apoptotic process
GO:0043276 IMP anoikis
GO:0046777 TAS protein autophosphorylation
GO:2001242 IMP regulation of intrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000061096 dapk2a protein_coding Danio_rerio
ENSMUSG00000032380 Dapk2 protein_coding Mus_musculus

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