ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: EPH receptor A3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000044524 EPHA3 9606 + 3:89107524-89482134 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000336596 EPHA3-001 89107524-89482134 protein_coding
  ENST00000452448 EPHA3-003 89107662-89400345 protein_coding
  ENST00000494014 EPHA3-002 89107676-89479659 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHUVECENST00000336596ENST00000452448ENST00000494014
Transcript ID BECs HAoEC HHSEC HUVEC
ENST00000336596 0.042±0.00 0.005±0.00 N/A 0.082±0.04
ENST00000452448 N/A 0.020±0.01 0.016±0.00 0.023±0.01
ENST00000494014 N/A 0.014±0.00 N/A N/A

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005003 IEA ephrin receptor activity
GO:0005004 IDA GPI-linked ephrin receptor activity
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005576 IEA extracellular region
GO:0005769 IDA early endosome
GO:0005887 IDA:IEA integral component of plasma membrane
GO:0006468 IEA protein phosphorylation
GO:0007155 IEA cell adhesion
GO:0007169 IEA transmembrane receptor protein tyrosine kinase signaling pathway
GO:0010717 ISS regulation of epithelial to mesenchymal transition
GO:0010976 IMP positive regulation of neuron projection development
GO:0016477 ISS cell migration
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0032319 IDA regulation of Rho GTPase activity
GO:0032956 IDA regulation of actin cytoskeleton organization
GO:0048013 IDA:IEA ephrin receptor signaling pathway
GO:0051893 IDA regulation of focal adhesion assembly
GO:0070507 IDA regulation of microtubule cytoskeleton organization
GO:0071300 IMP cellular response to retinoic acid
GO:0097155 ISS fasciculation of sensory neuron axon
GO:0097156 ISS fasciculation of motor neuron axon

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000039373 epha3 protein_coding Danio_rerio
ENSMUSG00000052504 Epha3 protein_coding Mus_musculus

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