ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: ubiquitin specific peptidase 28
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000048028 USP28 9606 - 11:113797874-113875570 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000003302 USP28-001 113797874-113875570 protein_coding
  ENST00000535607 USP28-011 113817706-113833517 nonsense_mediated_decay
  ENST00000537490 USP28-013 113817831-113830976 nonsense_mediated_decay
  ENST00000537642 USP28-009 113829221-113875496 protein_coding
  ENST00000537706 USP28-002 113813755-113875528 protein_coding
  ENST00000538224 USP28-014 113804928-113809175 protein_coding
  ENST00000538475 USP28-012 113812279-113833470 protein_coding
  ENST00000540438 USP28-005 113799062-113875566 nonsense_mediated_decay
  ENST00000540925 USP28-007 113852527-113875536 protein_coding
  ENST00000542033 USP28-003 113830883-113875533 processed_transcript
  ENST00000544272 USP28-015 113798979-113801701 retained_intron
  ENST00000544750 USP28-008 113852622-113875533 protein_coding
  ENST00000544967 USP28-006 113798092-113829467 protein_coding
  ENST00000545540 USP28-004 113798805-113875570 protein_coding
  ENST00000545608 USP28-010 113815264-113833552 nonsense_mediated_decay

Expression Patterns


Heat Map
Numeric Values
Transcript'; HAoECHMVEC-DHUVECENST00000003302ENST00000540438ENST00000542033ENST00000544967ENST00000545540
Transcript ID HAoEC HMVEC-D HUVEC
ENST00000003302 1.636±0.44 0.755±0.00 1.532±0.56
ENST00000540438 N/A N/A 0.114±0.00
ENST00000542033 N/A 5.631±0.00 3.831±4.27
ENST00000544967 2.990±1.58 3.791±0.00 2.406±1.10
ENST00000545540 2.462±0.93 N/A 1.831±0.90

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0002C0 CIL_0002C0_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000077 IMP DNA damage checkpoint
GO:0004221 IMP ubiquitin thiolesterase activity
GO:0004843 IDA ubiquitin-specific protease activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005654 IDA nucleoplasm
GO:0005730 IDA nucleolus
GO:0006281 IEA DNA repair
GO:0006511 IEA ubiquitin-dependent protein catabolic process
GO:0006974 IDA cellular response to DNA damage stimulus
GO:0008234 IEA cysteine-type peptidase activity
GO:0008283 IMP cell proliferation
GO:0010212 IDA response to ionizing radiation
GO:0016579 IDA protein deubiquitination
GO:0034644 IDA cellular response to UV
GO:0036459 IEA ubiquitinyl hydrolase activity
GO:0042771 IDA intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0043234 IDA protein complex

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000008880 usp28 protein_coding Danio_rerio
ENSMUSG00000032267 Usp28 protein_coding Mus_musculus

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