ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: solute carrier family 12 (sodium/potassium/chloride transporter), member 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000064651 SLC12A2 9606 + 5:128083766-128189688 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000262461 SLC12A2-001 128083766-128189688 protein_coding
  ENST00000343225 SLC12A2-004 128083848-128188442 protein_coding
  ENST00000502849 SLC12A2-007 128178380-128182921 retained_intron
  ENST00000504416 SLC12A2-002 128157988-128171095 retained_intron
  ENST00000507791 SLC12A2-006 128177549-128184507 processed_transcript
  ENST00000509205 SLC12A2-003 128083791-128187025 nonsense_mediated_decay
  ENST00000509616 SLC12A2-005 128158049-128171882 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000262461ENST00000343225ENST00000509205
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000262461 0.388±0.00 5.598±3.35 0.231±0.00 26.844±0.00 9.462±7.15
ENST00000343225 N/A 4.878±2.54 N/A N/A 2.624±1.84
ENST00000509205 N/A 6.258±3.61 N/A 27.297±0.00 3.136±1.98

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0006CW CIL_0006CW_0002 CGP
CIL_00041L CIL_00041L_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006810 TAS:IEA transport
GO:0006811 TAS:IEA ion transport
GO:0006813 IEA potassium ion transport
GO:0006814 IEA sodium ion transport
GO:0006821 IEA chloride transport
GO:0006972 IEA hyperosmotic response
GO:0007214 IEA gamma-aminobutyric acid signaling pathway
GO:0008511 IEA sodium:potassium:chloride symporter activity
GO:0008519 IDA ammonium transmembrane transporter activity
GO:0015377 IEA cation:chloride symporter activity
GO:0015696 IDA ammonium transport
GO:0016020 TAS:IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016323 IEA basolateral plasma membrane
GO:0016324 IEA apical plasma membrane
GO:0030321 IDA transepithelial chloride transport
GO:0031982 IDA vesicle
GO:0035264 IEA multicellular organism growth
GO:0045795 IEA positive regulation of cell volume
GO:0050910 IEA detection of mechanical stimulus involved in sensory perception of sound
GO:0055085 TAS:IEA transmembrane transport
GO:0060444 IEA branching involved in mammary gland duct morphogenesis
GO:0060763 IEA mammary duct terminal end bud growth
GO:0070062 IDA extracellular vesicular exosome
GO:0070634 IDA transepithelial ammonium transport
GO:0072488 IDA ammonium transmembrane transport
GO:1902476 IEA chloride transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000086870 slc12a2 protein_coding Danio_rerio
ENSMUSG00000024597 Slc12a2 protein_coding Mus_musculus

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