ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: SP100 nuclear antigen
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000067066 SP100 9606 + 2:230415942-230544090 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000264052 SP100-001 230415942-230516527 protein_coding
  ENST00000340126 SP100-002 230416266-230543183 protein_coding
  ENST00000409112 SP100-004 230416266-230508146 protein_coding
  ENST00000409341 SP100-006 230416247-230470517 protein_coding
  ENST00000409824 SP100-008 230416240-230470489 protein_coding
  ENST00000409897 SP100-005 230416756-230470530 protein_coding
  ENST00000413284 SP100-016 230462435-230470103 protein_coding
  ENST00000427101 SP100-201 230416156-230470534 protein_coding
  ENST00000431952 SP100-003 230504262-230544090 protein_coding
  ENST00000432979 SP100-010 230416221-230449380 protein_coding
  ENST00000452345 SP100-017 230462467-230494460 protein_coding
  ENST00000459786 SP100-018 230504217-230506766 retained_intron
  ENST00000462751 SP100-013 230463618-230467147 retained_intron
  ENST00000466710 SP100-012 230449569-230462629 retained_intron
  ENST00000470940 SP100-011 230449375-230461328 retained_intron
  ENST00000488180 SP100-009 230537642-230544090 retained_intron
  ENST00000492546 SP100-019 230473117-230498522 retained_intron
  ENST00000494508 SP100-015 230468832-230470360 retained_intron
  ENST00000494901 SP100-007 230508146-230543122 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsCECsHAoECHHSECHMVEC-DHUVECENST00000264052ENST00000340126ENST00000409112ENST00000409341ENST00000409824ENST00000413284ENST00000427101ENST00000431952ENST00000494508ENST00000494901
Transcript ID BECs CECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000264052 N/A N/A 3.301±1.80 N/A N/A 5.051±2.31
ENST00000340126 N/A N/A N/A N/A N/A 0.047±0.00
ENST00000409112 4.826±0.00 N/A 5.915±2.72 N/A N/A 8.082±3.22
ENST00000409341 19.657±0.00 N/A 16.344±3.81 12.466±0.00 49.067±0.00 19.203±12.35
ENST00000409824 N/A N/A N/A N/A N/A 7.245±1.47
ENST00000413284 63.459±0.00 N/A N/A N/A N/A N/A
ENST00000427101 N/A N/A N/A N/A N/A 9.422±2.53
ENST00000431952 N/A N/A 3.256±0.68 N/A N/A 9.256±0.00
ENST00000494508 62.821±4.02 N/A N/A 50.402±0.00 N/A N/A
ENST00000494901 3.185±0.00 895.594±482.38 N/A N/A N/A 1.518±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0004AU CIL_0004AU_0004 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000723 IMP telomere maintenance
GO:0003677 IEA DNA binding
GO:0003713 IDA transcription coactivator activity
GO:0003714 IDA transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 IDA:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005730 IMP nucleolus
GO:0005737 IDA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006978 IDA DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
GO:0008134 IPI transcription factor binding
GO:0008270 IEA zinc ion binding
GO:0010596 IMP negative regulation of endothelial cell migration
GO:0016032 IEA viral process
GO:0016605 IDA PML body
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0019900 IPI kinase binding
GO:0019904 IPI protein domain specific binding
GO:0030870 IDA Mre11 complex
GO:0032526 IDA response to retinoic acid
GO:0032897 IDA negative regulation of viral transcription
GO:0034097 IDA response to cytokine
GO:0034340 IDA response to type I interferon
GO:0034341 IMP response to interferon-gamma
GO:0034399 IDA nuclear periphery
GO:0042802 IPI identical protein binding
GO:0042803 IPI protein homodimerization activity
GO:0043392 IDA negative regulation of DNA binding
GO:0043433 IDA negative regulation of sequence-specific DNA binding transcription factor activity
GO:0045765 IMP regulation of angiogenesis
GO:0045892 IMP negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0046826 IMP negative regulation of protein export from nucleus
GO:0048384 IC retinoic acid receptor signaling pathway
GO:0051091 IDA positive regulation of sequence-specific DNA binding transcription factor activity
GO:0051271 IMP negative regulation of cellular component movement
GO:0060333 IC interferon-gamma-mediated signaling pathway
GO:0060337 IC type I interferon signaling pathway
GO:0070087 IPI chromo shadow domain binding
GO:1902041 IMP regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:1902044 IMP regulation of Fas signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000038133 zgc:113411 protein_coding Danio_rerio
ENSDARG00000055359 si:dkey-68o6.2 protein_coding Danio_rerio
ENSDARG00000090449 si:dkey-68o6.4 protein_coding Danio_rerio
ENSMUSG00000026222 Sp100 protein_coding Mus_musculus
ENSMUSG00000094514 AC133103.3 protein_coding Mus_musculus
ENSMUSG00000094915 AC168977.2 protein_coding Mus_musculus

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