ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: guanine nucleotide binding protein (G protein), beta 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000069966 GNB5 9606 - 15:52115105-52191369 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000261837 GNB5-001 52115105-52191369 protein_coding
  ENST00000358784 GNB5-002 52122206-52180001 protein_coding
  ENST00000396335 GNB5-004 52120939-52179887 protein_coding
  ENST00000557936 GNB5-006 52121626-52128795 retained_intron
  ENST00000558122 GNB5-009 52141206-52144461 processed_transcript
  ENST00000558519 GNB5-010 52124473-52141211 nonsense_mediated_decay
  ENST00000559348 GNB5-005 52122209-52139955 processed_transcript
  ENST00000559541 GNB5-011 52124539-52135847 retained_intron
  ENST00000560075 GNB5-008 52147167-52191334 retained_intron
  ENST00000560085 GNB5-012 52123559-52128273 retained_intron
  ENST00000560116 GNB5-003 52149278-52179900 protein_coding
  ENST00000561313 GNB5-007 52135689-52179973 nonsense_mediated_decay

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000261837ENST00000358784ENST00000396335ENST00000561313
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000261837 0.335±0.00 0.484±0.15 0.187±0.00 0.961±0.00 0.345±0.10
ENST00000358784 N/A 8.923±3.72 N/A 13.016±0.00 5.297±2.76
ENST00000396335 6.681±1.51 2.924±1.44 2.416±0.00 3.523±0.00 1.816±0.90
ENST00000561313 N/A 9.615±1.35 N/A N/A 7.001±1.81

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003924 NAS GTPase activity
GO:0004871 NAS signal transducer activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IEA nucleus
GO:0005886 IEA plasma membrane
GO:0006184 NAS GTP catabolic process
GO:0007165 NAS signal transduction
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007603 TAS phototransduction, visible light
GO:0016056 TAS rhodopsin mediated signaling pathway
GO:0022400 TAS regulation of rhodopsin mediated signaling pathway
GO:0031682 IPI G-protein gamma-subunit binding
GO:0051087 IPI chaperone binding
GO:1901386 IDA negative regulation of voltage-gated calcium channel activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000055377 gnb5b protein_coding Danio_rerio
ENSMUSG00000032192 Gnb5 protein_coding Mus_musculus

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