ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: protein tyrosine phosphatase, non-receptor type 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000070159 PTPN3 9606 - 9:109375466-109498313 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000262539 PTPN3-201 109375694-109498313 protein_coding
  ENST00000374541 PTPN3-001 109375700-109498306 protein_coding
  ENST00000412145 PTPN3-202 109375694-109451384 protein_coding
  ENST00000446349 PTPN3-203 109375694-109451384 protein_coding
  ENST00000447271 PTPN3-003 109375466-109378980 processed_transcript
  ENST00000497739 PTPN3-002 109389237-109397770 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000262539ENST00000374541ENST00000412145ENST00000446349ENST00000447271ENST00000497739
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000262539 N/A 0.239±0.00 N/A N/A 0.001±0.00
ENST00000374541 0.096±0.00 0.213±0.25 N/A 0.730±0.00 0.021±0.03
ENST00000412145 N/A 0.027±0.00 N/A N/A N/A
ENST00000446349 N/A 0.010±0.00 N/A 0.130±0.00 0.010±0.01
ENST00000447271 N/A 0.154±0.01 1.414±0.00 N/A 0.228±0.14
ENST00000497739 N/A 0.087±0.03 N/A N/A 0.093±0.03

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0001IY CIL_0001IY_0001 CGP
CIL_0001GE CIL_0001GE_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001784 IPI phosphotyrosine binding
GO:0004725 IEA protein tyrosine phosphatase activity
GO:0005515 IEA protein binding
GO:0005737 IDA cytoplasm
GO:0005856 IEA cytoskeleton
GO:0006470 IEA protein dephosphorylation
GO:0008092 IEA cytoskeletal protein binding
GO:0008138 IEA protein tyrosine/serine/threonine phosphatase activity
GO:0009898 IDA cytoplasmic side of plasma membrane
GO:0016311 IEA dephosphorylation
GO:0016791 IEA phosphatase activity
GO:0017080 IDA sodium channel regulator activity
GO:0035335 IEA peptidyl-tyrosine dephosphorylation
GO:0045930 IDA negative regulation of mitotic cell cycle
GO:0051045 IMP negative regulation of membrane protein ectodomain proteolysis
GO:0051117 IPI ATPase binding
GO:0097421 IEA liver regeneration
GO:0098902 IDA regulation of membrane depolarization during action potential
GO:2000649 IDA regulation of sodium ion transmembrane transporter activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000055784 ptpn3 protein_coding Danio_rerio
ENSMUSG00000038764 Ptpn3 protein_coding Mus_musculus

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