ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: MAX network transcriptional repressor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000070444 MNT 9606 - 17:2384060-2401118 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000174618 MNT-001 2384060-2401118 protein_coding
  ENST00000571232 MNT-004 2387498-2393830 processed_transcript
  ENST00000571836 MNT-003 2395330-2396853 processed_transcript
  ENST00000572892 MNT-005 2387344-2392760 processed_transcript
  ENST00000573384 MNT-007 2387564-2388298 retained_intron
  ENST00000574559 MNT-002 2395014-2400446 processed_transcript
  ENST00000575374 MNT-008 2387320-2391815 processed_transcript
  ENST00000575394 MNT-006 2387909-2401104 protein_coding
  ENST00000575402 MNT-009 2389266-2392078 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000174618ENST00000575394ENST00000575402
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000174618 0.495±0.00 1.702±0.97 0.530±0.00 2.316±0.00 2.664±1.71
ENST00000575394 N/A N/A N/A N/A 19.198±7.30
ENST00000575402 N/A 0.331±0.00 N/A N/A 1.139±0.52

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00093G CIL_00093G_0001 VISTA
CIL_0007RP CIL_0007RP_0001 VISTA

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000977 IDA RNA polymerase II regulatory region sequence-specific DNA binding
GO:0001227 IDA RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0003677 IEA DNA binding
GO:0003682 IEA chromatin binding
GO:0003700 TAS sequence-specific DNA binding transcription factor activity
GO:0003713 TAS transcription coactivator activity
GO:0003714 TAS transcription corepressor activity
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006366 TAS transcription from RNA polymerase II promoter
GO:0007275 TAS multicellular organismal development
GO:0007569 IEA cell aging
GO:0008285 TAS negative regulation of cell proliferation
GO:0046983 IEA protein dimerization activity
GO:0051726 IEA regulation of cell cycle
GO:2001234 IEA negative regulation of apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000073988 mntb protein_coding Danio_rerio
ENSMUSG00000000282 Mnt protein_coding Mus_musculus

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