ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: polymerase (DNA directed), beta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000070501 POLB 9606 + 8:42338454-42371808 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000265421 POLB-001 42338455-42371808 protein_coding
  ENST00000517393 POLB-011 42361298-42371808 protein_coding
  ENST00000518579 POLB-016 42357174-42371752 protein_coding
  ENST00000518925 POLB-005 42338482-42369297 protein_coding
  ENST00000519094 POLB-003 42338494-42339380 retained_intron
  ENST00000519524 POLB-010 42355459-42361712 retained_intron
  ENST00000519771 POLB-014 42338605-42369329 nonsense_mediated_decay
  ENST00000520008 POLB-002 42338459-42361361 protein_coding
  ENST00000521290 POLB-008 42349039-42371808 protein_coding
  ENST00000521418 POLB-013 42369607-42371808 retained_intron
  ENST00000521492 POLB-012 42368936-42371808 protein_coding
  ENST00000522297 POLB-004 42338494-42349289 retained_intron
  ENST00000522610 POLB-015 42338507-42371765 nonsense_mediated_decay
  ENST00000523465 POLB-009 42357198-42357942 retained_intron
  ENST00000524208 POLB-007 42344960-42369988 nonsense_mediated_decay
  ENST00000530566 POLB-018 42338494-42340147 processed_transcript
  ENST00000532157 POLB-006 42338454-42357203 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000265421ENST00000517393ENST00000518579ENST00000518925ENST00000519771ENST00000520008ENST00000521290ENST00000521418ENST00000521492ENST00000522297ENST00000522610ENST00000524208ENST00000532157
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000265421 1.951±0.00 9.430±7.83 N/A 2.506±0.00 5.460±2.22
ENST00000517393 14.615±0.00 22.974±18.34 18.248±0.00 N/A 5.150±0.00
ENST00000518579 N/A 2.802±0.00 N/A N/A N/A
ENST00000518925 4.066±0.00 N/A N/A 2.916±0.00 2.620±0.25
ENST00000519771 4.822±0.00 3.038±0.00 N/A N/A N/A
ENST00000520008 N/A 8.777±7.71 N/A N/A 4.211±1.54
ENST00000521290 8.717±3.74 6.155±4.29 5.424±0.00 4.490±0.00 2.718±0.11
ENST00000521418 N/A N/A 15.826±0.00 N/A N/A
ENST00000521492 5.112±0.00 N/A 13.213±0.00 N/A 4.301±0.77
ENST00000522297 N/A N/A N/A N/A 5.339±0.37
ENST00000522610 N/A N/A N/A 2.743±0.00 N/A
ENST00000524208 N/A 11.517±8.21 N/A N/A N/A
ENST00000532157 N/A N/A N/A N/A 5.570±2.18

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0003684 IEA damaged DNA binding
GO:0003887 IDA:IEA DNA-directed DNA polymerase activity
GO:0005515 IPI protein binding
GO:0005634 IDA:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005874 IDA microtubule
GO:0005876 IDA spindle microtubule
GO:0006261 TAS DNA-dependent DNA replication
GO:0006281 TAS:IEA DNA repair
GO:0006284 IDA base-excision repair
GO:0006287 IEA base-excision repair, gap-filling
GO:0006290 IEA pyrimidine dimer repair
GO:0006974 IMP cellular response to DNA damage stimulus
GO:0008017 IDA microtubule binding
GO:0008630 IEA intrinsic apoptotic signaling pathway in response to DNA damage
GO:0016829 IDA lyase activity
GO:0019899 IPI enzyme binding
GO:0034061 IEA DNA polymerase activity
GO:0045471 IEA response to ethanol
GO:0046872 IEA metal ion binding
GO:0051402 IEA neuron apoptotic process
GO:0071897 IEA DNA biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000003749 polb protein_coding Danio_rerio
ENSMUSG00000031536 Polb protein_coding Mus_musculus

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