ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: mitogen-activated protein kinase kinase kinase kinase 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000071054 MAP4K4 9606 + 2:101696850-101894689 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000302217 MAP4K4-201 101698026-101894689 protein_coding
  ENST00000324219 MAP4K4-202 101697703-101894689 protein_coding
  ENST00000347699 MAP4K4-001 101698081-101891321 protein_coding
  ENST00000350198 MAP4K4-203 101697703-101894689 protein_coding
  ENST00000350878 MAP4K4-204 101697703-101894689 protein_coding
  ENST00000413150 MAP4K4-003 101698026-101894687 protein_coding
  ENST00000417294 MAP4K4-004 101698530-101891987 protein_coding
  ENST00000418101 MAP4K4-011 101855977-101865003 protein_coding
  ENST00000421882 MAP4K4-006 101839828-101891496 protein_coding
  ENST00000425019 MAP4K4-002 101697744-101891496 protein_coding
  ENST00000427603 MAP4K4-008 101696850-101824053 protein_coding
  ENST00000456652 MAP4K4-005 101698081-101891987 protein_coding
  ENST00000476609 MAP4K4-007 101825402-101862240 retained_intron
  ENST00000477711 MAP4K4-012 101866493-101867730 retained_intron
  ENST00000489490 MAP4K4-010 101825319-101829754 retained_intron
  ENST00000491743 MAP4K4-014 101867856-101870085 retained_intron
  ENST00000496989 MAP4K4-009 101797234-101831816 processed_transcript
  ENST00000498066 MAP4K4-013 101867536-101870633 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsCECsHAoECHHSECHMVEC-DHUVECENST00000302217ENST00000347699ENST00000350198ENST00000350878ENST00000413150ENST00000417294ENST00000421882ENST00000425019ENST00000456652
Transcript ID BECs CECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000302217 10.387±0.44 39.137±0.00 N/A 3.744±0.00 N/A 14.077±8.94
ENST00000347699 N/A N/A 16.941±10.59 N/A 18.369±0.00 33.653±16.94
ENST00000350198 4.613±0.00 N/A N/A N/A N/A 7.578±2.70
ENST00000350878 N/A N/A N/A N/A N/A 7.326±2.03
ENST00000413150 N/A N/A 3.790±0.00 N/A N/A 9.555±3.35
ENST00000417294 N/A N/A 4.389±0.00 N/A N/A 19.700±10.39
ENST00000421882 18.285±0.00 N/A N/A N/A N/A N/A
ENST00000425019 N/A N/A 20.795±12.64 N/A 28.216±0.00 20.660±14.21
ENST00000456652 15.929±3.54 N/A 19.981±10.13 N/A N/A 20.533±10.29

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0004QW CIL_0004QW_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004674 IDA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005083 IEA small GTPase regulator activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005737 IDA cytoplasm
GO:0006468 IEA protein phosphorylation
GO:0010977 IEA negative regulation of neuron projection development
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0035556 IDA intracellular signal transduction
GO:0046328 IDA regulation of JNK cascade
GO:0050790 IEA regulation of catalytic activity
GO:0061179 IEA negative regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0070571 IEA negative regulation of neuron projection regeneration

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000026074 Map4k4 protein_coding Mus_musculus

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