ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: methyl-CpG binding domain protein 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000071655 MBD3 9606 - 19:1573596-1592801 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000156825 MBD3-002 1573596-1592801 protein_coding
  ENST00000434436 MBD3-001 1576678-1592708 protein_coding
  ENST00000585903 MBD3-006 1581108-1584573 nonsense_mediated_decay
  ENST00000585967 MBD3-004 1581159-1592359 protein_coding
  ENST00000589064 MBD3-010 1577746-1585333 processed_transcript
  ENST00000589901 MBD3-011 1578445-1581737 retained_intron
  ENST00000590550 MBD3-009 1576640-1585530 protein_coding
  ENST00000590830 MBD3-008 1578012-1584954 retained_intron
  ENST00000592012 MBD3-007 1576640-1585307 nonsense_mediated_decay
  ENST00000592361 MBD3-005 1581210-1586362 protein_coding
  ENST00000592965 MBD3-003 1585055-1592392 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000434436ENST00000592012
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000434436 45.225±0.00 14.766±5.35 33.240±0.00 19.002±0.00 28.295±23.00
ENST00000592012 103.887±0.00 21.509±9.70 66.151±0.00 18.756±0.00 15.740±6.04

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0003YO CIL_0003YO_0001 CGP
CIL_0003Z8 CIL_0003Z8_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000785 IEA chromatin
GO:0000790 IDA nuclear chromatin
GO:0000792 IEA heterochromatin
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000980 IDA RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0001701 IEA in utero embryonic development
GO:0003677 TAS:IEA DNA binding
GO:0003682 IEA chromatin binding
GO:0005488 IEA binding
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0006346 IEA methylation-dependent chromatin silencing
GO:0006351 IEA transcription, DNA-templated
GO:0008327 IDA methyl-CpG binding
GO:0009888 IEA tissue development
GO:0016573 IEA histone acetylation
GO:0016581 NAS NuRD complex
GO:0031492 IDA nucleosomal DNA binding
GO:0043044 IDA ATP-dependent chromatin remodeling
GO:0043234 IDA protein complex

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000042029 mbd3b protein_coding Danio_rerio
ENSDARG00000061774 mbd3a protein_coding Danio_rerio
ENSMUSG00000035478 Mbd3 protein_coding Mus_musculus

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