ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: actinin, alpha 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000072110 ACTN1 9606 - 14:68874143-68979440 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000193403 ACTN1-001 68874143-68979440 protein_coding
  ENST00000376839 ACTN1-007 68874783-68977566 protein_coding
  ENST00000394419 ACTN1-005 68874323-68979239 protein_coding
  ENST00000438964 ACTN1-002 68874686-68979262 protein_coding
  ENST00000538545 ACTN1-006 68874859-68979076 protein_coding
  ENST00000544964 ACTN1-019 68879046-68890142 protein_coding
  ENST00000553290 ACTN1-020 68879049-68884303 protein_coding
  ENST00000553370 ACTN1-015 68904702-68977654 protein_coding
  ENST00000553659 ACTN1-013 68925559-68978269 protein_coding
  ENST00000553779 ACTN1-016 68910020-68947548 protein_coding
  ENST00000553882 ACTN1-009 68874323-68879022 retained_intron
  ENST00000554158 ACTN1-017 68902543-68921359 processed_transcript
  ENST00000554508 ACTN1-018 68893703-68921038 processed_transcript
  ENST00000555075 ACTN1-022 68874786-68882567 protein_coding
  ENST00000555616 ACTN1-012 68892228-68978289 protein_coding
  ENST00000556083 ACTN1-008 68874318-68888263 retained_intron
  ENST00000556203 ACTN1-010 68973781-68979031 processed_transcript
  ENST00000556343 ACTN1-021 68883265-68884295 processed_transcript
  ENST00000556432 ACTN1-023 68879864-68881122 retained_intron
  ENST00000556433 ACTN1-011 68893665-68978735 protein_coding
  ENST00000556571 ACTN1-014 68910022-68978240 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000193403ENST00000394419ENST00000438964ENST00000553882ENST00000555075
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000193403 22.561±0.00 67.591±17.51 N/A 87.074±0.00 99.338±49.38
ENST00000394419 N/A 56.311±24.85 N/A 55.262±0.00 56.893±0.00
ENST00000438964 23.199±0.00 42.520±24.91 N/A N/A 38.602±19.85
ENST00000553882 N/A N/A 29.702±0.00 N/A 41.825±5.42
ENST00000555075 135.990±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0002CK CIL_0002CK_0001 CGP
CIL_0001JZ CIL_0001JZ_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001725 IEA stress fiber
GO:0002576 TAS platelet degranulation
GO:0003725 IDA double-stranded RNA binding
GO:0005178 IDA integrin binding
GO:0005509 IEA calcium ion binding
GO:0005515 IPI:IEA protein binding
GO:0005576 TAS extracellular region
GO:0005615 IDA extracellular space
GO:0005634 IEA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005856 IEA cytoskeleton
GO:0005886 IEA plasma membrane
GO:0005916 IEA fascia adherens
GO:0005925 IMP focal adhesion
GO:0007596 TAS blood coagulation
GO:0017166 IPI vinculin binding
GO:0019904 IEA protein domain specific binding
GO:0030018 IEA Z disc
GO:0030168 TAS platelet activation
GO:0030198 TAS extracellular matrix organization
GO:0030864 IEA cortical actin cytoskeleton
GO:0031093 TAS platelet alpha granule lumen
GO:0031143 TAS pseudopodium
GO:0034329 TAS cell junction assembly
GO:0042981 NAS regulation of apoptotic process
GO:0042995 IDA cell projection
GO:0043197 IEA dendritic spine
GO:0044325 IPI ion channel binding
GO:0048041 IMP focal adhesion assembly
GO:0051015 IEA actin filament binding
GO:0051017 IEA actin filament bundle assembly
GO:0051271 IMP negative regulation of cellular component movement
GO:0051764 IEA actin crosslink formation
GO:0070062 IDA extracellular vesicular exosome
GO:0070830 IEA tight junction assembly
GO:1902396 IEA protein localization to tight junction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000007219 actn1 protein_coding Danio_rerio
ENSMUSG00000015143 Actn1 protein_coding Mus_musculus

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