ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000072609 CHFR 9606 - 12:132822187-132956304 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000266880 CHFR-001 132832357-132887598 protein_coding
  ENST00000315585 CHFR-010 132840910-132883017 nonsense_mediated_decay
  ENST00000432561 CHFR-002 132840975-132887608 protein_coding
  ENST00000443047 CHFR-004 132840352-132887603 protein_coding
  ENST00000450056 CHFR-003 132840352-132887623 protein_coding
  ENST00000499045 CHFR-011 132877561-132909186 processed_transcript
  ENST00000502279 CHFR-023 132848155-132849960 retained_intron
  ENST00000511001 CHFR-019 132853637-132855055 processed_transcript
  ENST00000535181 CHFR-016 132871905-132887564 retained_intron
  ENST00000535527 CHFR-021 132841373-132856565 nonsense_mediated_decay
  ENST00000535897 CHFR-018 132859079-132861904 retained_intron
  ENST00000536196 CHFR-017 132871973-132887572 processed_transcript
  ENST00000536843 CHFR-008 132840349-132848991 retained_intron
  ENST00000536932 CHFR-027 132869724-132956304 protein_coding
  ENST00000537551 CHFR-015 132870725-132887522 processed_transcript
  ENST00000538235 CHFR-022 132841393-132853489 processed_transcript
  ENST00000540537 CHFR-005 132869619-132909147 protein_coding
  ENST00000540963 CHFR-014 132861547-132887532 protein_coding
  ENST00000541341 CHFR-028 132822187-132848192 retained_intron
  ENST00000541817 CHFR-012 132859185-132904894 protein_coding
  ENST00000542714 CHFR-013 132869639-132904873 protein_coding
  ENST00000544093 CHFR-020 132841125-132851658 nonsense_mediated_decay
  ENST00000544268 CHFR-007 132840405-132854104 retained_intron
  ENST00000545046 CHFR-009 132840352-132847802 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHUVECENST00000443047ENST00000450056ENST00000544268ENST00000545046
Transcript ID BECs HAoEC HHSEC HUVEC
ENST00000443047 N/A 11.442±0.94 14.742±0.00 11.022±0.00
ENST00000450056 N/A N/A N/A 15.975±5.39
ENST00000544268 N/A N/A 14.365±0.00 N/A
ENST00000545046 16.390±1.51 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00006K CIL_00006K_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IDA nucleotide binding
GO:0000209 IDA protein polyubiquitination
GO:0000278 IEA mitotic cell cycle
GO:0004842 IDA ubiquitin-protein transferase activity
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0006511 IEA ubiquitin-dependent protein catabolic process
GO:0007067 IEA mitotic nuclear division
GO:0007093 TAS mitotic cell cycle checkpoint
GO:0008270 IEA zinc ion binding
GO:0016605 IDA PML body
GO:0016874 IEA ligase activity
GO:0019941 IDA modification-dependent protein catabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000075347 chfr protein_coding Danio_rerio
ENSMUSG00000014668 Chfr protein_coding Mus_musculus

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