ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: acetyl-CoA carboxylase beta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000076555 ACACB 9606 + 12:109116595-109268226 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000338432 ACACB-001 109116595-109268226 protein_coding
  ENST00000377848 ACACB-201 109139397-109268223 protein_coding
  ENST00000377854 ACACB-202 109139397-109260147 protein_coding
  ENST00000396233 ACACB-012 109248958-109253061 retained_intron
  ENST00000534852 ACACB-011 109241223-109242667 retained_intron
  ENST00000536440 ACACB-013 109245714-109252578 nonsense_mediated_decay
  ENST00000537279 ACACB-014 109263022-109266941 retained_intron
  ENST00000537347 ACACB-010 109241670-109246386 retained_intron
  ENST00000538526 ACACB-004 109232669-109266555 nonsense_mediated_decay
  ENST00000539864 ACACB-005 109131358-109139910 protein_coding
  ENST00000542524 ACACB-009 109235307-109236377 retained_intron
  ENST00000543080 ACACB-007 109175977-109180040 processed_transcript
  ENST00000544651 ACACB-008 109191478-109191918 retained_intron
  ENST00000544726 ACACB-002 109154682-109172311 protein_coding
  ENST00000546328 ACACB-006 109139979-109167280 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000338432ENST00000377848ENST00000377854ENST00000396233ENST00000537279ENST00000538526ENST00000544651ENST00000544726
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000338432 N/A 0.101±0.00 N/A 0.060±0.00
ENST00000377848 0.054±0.00 0.121±0.10 0.062±0.00 0.188±0.31
ENST00000377854 N/A 0.179±0.02 0.049±0.00 0.139±0.08
ENST00000396233 0.098±0.00 0.251±0.00 0.468±0.00 0.283±0.06
ENST00000537279 N/A N/A N/A 0.185±0.07
ENST00000538526 N/A N/A N/A 0.178±0.21
ENST00000544651 N/A 1.586±0.01 N/A N/A
ENST00000544726 N/A N/A N/A 0.263±0.06

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00041E CIL_00041E_0001 CGP
CIL_0001VV CIL_0001VV_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003824 IEA catalytic activity
GO:0003989 IDA:IEA acetyl-CoA carboxylase activity
GO:0004075 IEA biotin carboxylase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005739 IDA mitochondrion
GO:0005741 TAS mitochondrial outer membrane
GO:0005829 TAS cytosol
GO:0006084 IDA acetyl-CoA metabolic process
GO:0006112 TAS energy reserve metabolic process
GO:0006633 IEA fatty acid biosynthetic process
GO:0006766 TAS vitamin metabolic process
GO:0006767 TAS water-soluble vitamin metabolic process
GO:0006768 TAS biotin metabolic process
GO:0006853 TAS carnitine shuttle
GO:0008152 IEA metabolic process
GO:0009374 IEA biotin binding
GO:0010884 IEA positive regulation of lipid storage
GO:0014070 IEA response to organic cyclic compound
GO:0016874 IEA ligase activity
GO:0031325 TAS positive regulation of cellular metabolic process
GO:0042493 IEA response to drug
GO:0044255 TAS cellular lipid metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0046322 IEA negative regulation of fatty acid oxidation
GO:0046872 IEA metal ion binding
GO:0051289 IDA protein homotetramerization
GO:0060421 IEA positive regulation of heart growth
GO:2001295 IEA malonyl-CoA biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000061994 acacb protein_coding Danio_rerio
ENSMUSG00000042010 Acacb protein_coding Mus_musculus

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