ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: THO complex 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000079134 THOC1 9606 - 18:214520-268050 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000261600 THOC1-001 214521-268027 protein_coding
  ENST00000577429 THOC1-018 214521-215778 retained_intron
  ENST00000577552 THOC1-019 224084-247951 retained_intron
  ENST00000578224 THOC1-008 263493-268019 retained_intron
  ENST00000578529 THOC1-012 214521-261162 retained_intron
  ENST00000579232 THOC1-010 214520-268019 retained_intron
  ENST00000579891 THOC1-020 216486-246433 protein_coding
  ENST00000580038 THOC1-013 214521-268022 nonsense_mediated_decay
  ENST00000580544 THOC1-004 265089-268019 retained_intron
  ENST00000580870 THOC1-003 264940-268019 retained_intron
  ENST00000581116 THOC1-006 259180-268045 nonsense_mediated_decay
  ENST00000581269 THOC1-005 254281-268050 nonsense_mediated_decay
  ENST00000581576 THOC1-009 259236-260218 retained_intron
  ENST00000582313 THOC1-016 244948-268027 processed_transcript
  ENST00000583228 THOC1-007 214521-245734 retained_intron
  ENST00000584470 THOC1-011 214522-226402 retained_intron
  ENST00000584642 THOC1-014 246068-252577 protein_coding
  ENST00000585307 THOC1-017 216209-219006 retained_intron
  ENST00000616322 THOC1-201 214522-268019 protein_coding
  ENST00000621904 THOC1-202 225289-265536 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; HHSECHMVEC-DHUVECENST00000261600ENST00000577429ENST00000579232
Transcript ID HHSEC HMVEC-D HUVEC
ENST00000261600 N/A 13.694±0.00 8.259±3.95
ENST00000577429 42.889±0.00 N/A N/A
ENST00000579232 7.061±0.00 N/A N/A

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000018 IMP regulation of DNA recombination
GO:0000346 IDA transcription export complex
GO:0000347 IDA THO complex
GO:0000445 IDA THO complex part of transcription export complex
GO:0003677 IEA DNA binding
GO:0003723 IEA RNA binding
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006396 TAS RNA processing
GO:0006397 IEA mRNA processing
GO:0006406 IDA mRNA export from nucleus
GO:0006915 IDA apoptotic process
GO:0007165 IEA signal transduction
GO:0008380 IEA RNA splicing
GO:0031297 IMP replication fork processing
GO:0032784 IDA regulation of DNA-templated transcription, elongation
GO:0032786 IMP positive regulation of DNA-templated transcription, elongation
GO:0045171 IDA intercellular bridge
GO:0046784 IDA viral mRNA export from host cell nucleus
GO:0048297 ISS negative regulation of isotype switching to IgA isotypes
GO:2000002 IMP negative regulation of DNA damage checkpoint

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000088246 thoc1 protein_coding Danio_rerio
ENSMUSG00000024287 Thoc1 protein_coding Mus_musculus

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