ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: kelch-like ECH-associated protein 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000079999 KEAP1 9606 - 19:10486120-10503741 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000171111 KEAP1-001 10486120-10503741 protein_coding
  ENST00000393623 KEAP1-002 10486126-10502896 protein_coding
  ENST00000585845 KEAP1-010 10491999-10503558 nonsense_mediated_decay
  ENST00000588024 KEAP1-007 10491947-10499509 processed_transcript
  ENST00000590237 KEAP1-009 10486612-10489435 retained_intron
  ENST00000590593 KEAP1-008 10486718-10491880 nonsense_mediated_decay
  ENST00000591039 KEAP1-006 10499398-10502685 protein_coding
  ENST00000591419 KEAP1-005 10499395-10502687 protein_coding
  ENST00000592055 KEAP1-004 10492064-10503186 protein_coding
  ENST00000592478 KEAP1-003 10486125-10491720 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000171111ENST00000393623ENST00000590237ENST00000592055ENST00000592478
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000171111 N/A 2.458±0.60 N/A N/A 5.008±3.32
ENST00000393623 N/A 11.174±10.76 N/A 9.412±0.00 18.844±14.01
ENST00000590237 65.986±0.00 8.356±0.00 N/A N/A N/A
ENST00000592055 N/A 22.290±8.18 N/A N/A 9.842±7.65
ENST00000592478 75.442±10.22 18.703±1.76 27.179±0.00 N/A 12.515±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0004FB CIL_0004FB_0001 CGP
CIL_000777 CIL_000777_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001701 IEA in utero embryonic development
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005783 IEA endoplasmic reticulum
GO:0005815 IDA microtubule organizing center
GO:0005829 TAS cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0008134 IPI transcription factor binding
GO:0010499 IDA proteasomal ubiquitin-independent protein catabolic process
GO:0016567 IEA protein ubiquitination
GO:0030496 IDA midbody
GO:0031463 IDA Cul3-RING ubiquitin ligase complex
GO:0032436 TAS positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0043433 TAS negative regulation of sequence-specific DNA binding transcription factor activity
GO:0045604 IEA regulation of epidermal cell differentiation
GO:0071353 IEA cellular response to interleukin-4

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000074634 keap1b protein_coding Danio_rerio
ENSMUSG00000003308 Keap1 protein_coding Mus_musculus

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