ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000080709 KCNN2 9606 + 5:114360945-114496640 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000264773 KCNN2-201 114362319-114496497 protein_coding
  ENST00000503706 KCNN2-002 114433530-114496516 protein_coding
  ENST00000505491 KCNN2-004 114433578-114493442 nonsense_mediated_decay
  ENST00000506812 KCNN2-003 114486671-114496058 retained_intron
  ENST00000507750 KCNN2-005 114363107-114495946 processed_transcript
  ENST00000512097 KCNN2-001 114360945-114496640 protein_coding
  ENST00000610748 KCNN2-202 114362319-114496495 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000264773ENST00000503706ENST00000505491ENST00000506812ENST00000507750ENST00000512097ENST00000610748
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000264773 N/A 0.446±0.26 N/A 1.470±0.00 0.223±0.18
ENST00000503706 0.177±0.00 1.775±1.03 2.171±0.00 N/A 0.143±0.15
ENST00000505491 N/A 3.743±2.31 N/A N/A 0.077±0.00
ENST00000506812 N/A N/A N/A N/A 0.163±0.00
ENST00000507750 N/A 0.044±0.00 N/A N/A 0.616±0.73
ENST00000512097 0.048±0.00 0.347±0.29 0.388±0.00 N/A 0.128±0.15
ENST00000610748 0.180±0.00 0.027±0.01 N/A 0.795±0.00 0.097±0.07

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0004UP CIL_0004UP_0001 CGP
CIL_0004UO CIL_0004UO_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005216 IEA ion channel activity
GO:0005516 IBA:IEA calmodulin binding
GO:0005790 IEA smooth endoplasmic reticulum
GO:0005886 IBA plasma membrane
GO:0006811 IEA ion transport
GO:0006813 NAS:IEA potassium ion transport
GO:0007268 TAS synaptic transmission
GO:0015269 IDA:IEA calcium-activated potassium channel activity
GO:0016021 NAS:IEA integral component of membrane
GO:0016286 IBA:IEA small conductance calcium-activated potassium channel activity
GO:0030018 IEA Z disc
GO:0030315 IEA T-tubule
GO:0042803 IPI protein homodimerization activity
GO:0043025 IBA neuronal cell body
GO:0043197 IBA dendritic spine
GO:0051393 IPI alpha-actinin binding
GO:0071805 IDA potassium ion transmembrane transport
GO:1901379 IDA regulation of potassium ion transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000014939 KCNN2 protein_coding Danio_rerio
ENSMUSG00000054477 Kcnn2 protein_coding Mus_musculus

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