ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: acetoacetyl-CoA synthetase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000081760 AACS 9606 + 12:125065379-125143333 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000316519 AACS-001 125065379-125143320 protein_coding
  ENST00000316543 AACS-003 125105151-125143316 processed_transcript
  ENST00000398953 AACS-014 125135790-125136740 processed_transcript
  ENST00000418937 AACS-002 125065434-125107162 nonsense_mediated_decay
  ENST00000441247 AACS-010 125100894-125125036 retained_intron
  ENST00000536118 AACS-013 125125742-125136795 retained_intron
  ENST00000537477 AACS-008 125091013-125107154 processed_transcript
  ENST00000537564 AACS-009 125092480-125107268 processed_transcript
  ENST00000538851 AACS-012 125117567-125134853 retained_intron
  ENST00000539251 AACS-011 125114421-125142177 retained_intron
  ENST00000543665 AACS-004 125128546-125143319 retained_intron
  ENST00000545511 AACS-005 125119858-125143333 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000316519ENST00000536118ENST00000545511
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000316519 4.287±0.00 10.908±3.11 6.068±0.00 8.694±4.05
ENST00000536118 N/A N/A N/A 1.301±0.00
ENST00000545511 N/A 0.385±0.00 N/A 0.781±0.15

Conserved Regions

Region IDSub-RegionRegion Type
CIL_000397 CIL_000397_0001 CGP
CIL_0000CO CIL_0000CO_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001889 IEA liver development
GO:0003824 IEA catalytic activity
GO:0005524 IEA ATP binding
GO:0005737 IEA cytoplasm
GO:0006629 IEA lipid metabolic process
GO:0006631 IEA fatty acid metabolic process
GO:0007584 IEA response to nutrient
GO:0008152 IEA metabolic process
GO:0010243 IEA response to organonitrogen compound
GO:0014070 IEA response to organic cyclic compound
GO:0014074 IEA response to purine-containing compound
GO:0030729 IEA acetoacetate-CoA ligase activity
GO:0032024 IEA positive regulation of insulin secretion
GO:0034201 IEA response to oleic acid
GO:0042493 IEA response to drug
GO:0042594 IEA response to starvation
GO:0045471 IEA response to ethanol
GO:0047760 IEA butyrate-CoA ligase activity
GO:0050872 IEA white fat cell differentiation
GO:0060612 IEA adipose tissue development
GO:0071333 IEA cellular response to glucose stimulus
GO:0071394 IEA cellular response to testosterone stimulus
GO:0071397 IEA cellular response to cholesterol

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000012468 aacs protein_coding Danio_rerio
ENSMUSG00000029482 Aacs protein_coding Mus_musculus

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