ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: malic enzyme 2, NAD(+)-dependent, mitochondrial
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000082212 ME2 9606 + 18:50879049-50954257 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000321341 ME2-001 50879049-50954257 protein_coding
  ENST00000382927 ME2-002 50879120-50947890 protein_coding
  ENST00000585680 ME2-004 50925860-50947445 processed_transcript
  ENST00000589330 ME2-003 50917242-50920711 retained_intron
  ENST00000591925 ME2-005 50940130-50947154 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000321341ENST00000382927ENST00000585680ENST00000591925
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000321341 0.565±0.00 1.075±0.37 N/A 1.225±0.00 0.978±0.46
ENST00000382927 3.112±0.63 18.492±4.22 10.537±0.00 19.391±0.00 9.953±5.76
ENST00000585680 8.853±0.00 14.076±2.32 13.736±0.00 N/A 9.344±2.41
ENST00000591925 9.679±0.00 N/A N/A N/A N/A

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004471 IEA malate dehydrogenase (decarboxylating) (NAD+) activity
GO:0005739 IDA mitochondrion
GO:0006108 IEA malate metabolic process
GO:0008948 IEA oxaloacetate decarboxylase activity
GO:0009055 TAS electron carrier activity
GO:0043231 IDA intracellular membrane-bounded organelle
GO:0046872 IEA metal ion binding
GO:0051287 IEA NAD binding
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000024556 Me2 protein_coding Mus_musculus

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