ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: exportin 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000082898 XPO1 9606 - 2:61477849-61538626 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000401558 XPO1-001 61477849-61538283 protein_coding
  ENST00000404992 XPO1-006 61478338-61537110 protein_coding
  ENST00000406957 XPO1-004 61478700-61538248 protein_coding
  ENST00000420673 XPO1-019 61522611-61534278 protein_coding
  ENST00000422552 XPO1-018 61522626-61534512 protein_coding
  ENST00000428210 XPO1-005 61477934-61538231 nonsense_mediated_decay
  ENST00000436018 XPO1-009 61526471-61538626 protein_coding
  ENST00000437159 XPO1-024 61496994-61526518 nonsense_mediated_decay
  ENST00000443240 XPO1-008 61502006-61538626 protein_coding
  ENST00000449444 XPO1-016 61526462-61536588 protein_coding
  ENST00000451765 XPO1-015 61499765-61537117 protein_coding
  ENST00000457483 XPO1-017 61522630-61537640 protein_coding
  ENST00000460037 XPO1-027 61493638-61495573 retained_intron
  ENST00000461407 XPO1-007 61482625-61488663 retained_intron
  ENST00000468259 XPO1-022 61502290-61525775 processed_transcript
  ENST00000469337 XPO1-028 61492342-61492994 retained_intron
  ENST00000475744 XPO1-026 61496961-61498874 retained_intron
  ENST00000476585 XPO1-023 61502146-61526523 processed_transcript
  ENST00000481073 XPO1-014 61477935-61494743 retained_intron
  ENST00000481214 XPO1-020 61526067-61537694 processed_transcript
  ENST00000489954 XPO1-025 61499717-61502608 retained_intron
  ENST00000492182 XPO1-030 61482625-61485958 retained_intron
  ENST00000494468 XPO1-029 61485584-61488663 processed_transcript
  ENST00000495003 XPO1-021 61526151-61533968 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000401558ENST00000404992ENST00000406957ENST00000428210ENST00000481073ENST00000481214
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000401558 N/A 13.344±5.19 2.181±0.00 19.210±0.00 17.508±14.37
ENST00000404992 N/A N/A N/A N/A 3.750±0.00
ENST00000406957 N/A 12.914±12.83 N/A 12.017±0.00 13.473±7.52
ENST00000428210 N/A N/A N/A N/A 3.050±1.55
ENST00000481073 13.464±4.76 N/A 10.227±0.00 N/A 10.597±6.79
ENST00000481214 N/A N/A N/A N/A 34.312±4.38

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0007N6 CIL_0007N6_0001 UCNEbase
CIL_0000ZI CIL_0000ZI_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000055 IMP ribosomal large subunit export from nucleus
GO:0000056 IMP ribosomal small subunit export from nucleus
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000278 TAS mitotic cell cycle
GO:0000776 IDA kinetochore
GO:0003723 IEA RNA binding
GO:0005215 TAS transporter activity
GO:0005487 IMP nucleocytoplasmic transporter activity
GO:0005488 IEA binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005635 TAS nuclear envelope
GO:0005642 IDA annulate lamellae
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0006611 IMP protein export from nucleus
GO:0006886 IEA intracellular protein transport
GO:0007179 TAS transforming growth factor beta receptor signaling pathway
GO:0008536 IEA Ran GTPase binding
GO:0008565 IEA protein transporter activity
GO:0010467 TAS gene expression
GO:0010824 IEA regulation of centrosome duplication
GO:0016020 IDA membrane
GO:0016032 TAS viral process
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0019058 TAS viral life cycle
GO:0019904 IEA protein domain specific binding
GO:0030512 TAS negative regulation of transforming growth factor beta receptor signaling pathway
GO:0030529 IDA ribonucleoprotein complex
GO:0031965 IDA nuclear membrane
GO:0034504 IEA protein localization to nucleus
GO:0042176 IEA regulation of protein catabolic process
GO:0042493 IEA response to drug
GO:0043231 IDA intracellular membrane-bounded organelle
GO:0046825 IEA regulation of protein export from nucleus
GO:0051028 IEA mRNA transport
GO:0075733 TAS intracellular transport of virus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000063229 xpo1b protein_coding Danio_rerio
ENSDARG00000078041 xpo1a protein_coding Danio_rerio
ENSMUSG00000020290 Xpo1 protein_coding Mus_musculus

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