ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: cylindromatosis (turban tumor syndrome)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000083799 CYLD 9606 + 16:50742050-50801935 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000311559 CYLD-003 50742074-50798617 protein_coding
  ENST00000398568 CYLD-005 50742120-50796882 protein_coding
  ENST00000427738 CYLD-010 50742760-50801935 protein_coding
  ENST00000562884 CYLD-015 50793617-50794888 protein_coding
  ENST00000563629 CYLD-008 50749963-50787746 retained_intron
  ENST00000563976 CYLD-013 50776201-50778294 retained_intron
  ENST00000564326 CYLD-006 50742081-50796711 protein_coding
  ENST00000564634 CYLD-012 50742118-50749798 protein_coding
  ENST00000566024 CYLD-014 50794294-50801933 protein_coding
  ENST00000566206 CYLD-002 50742086-50795724 protein_coding
  ENST00000566679 CYLD-007 50742110-50754424 protein_coding
  ENST00000568704 CYLD-009 50749549-50797334 protein_coding
  ENST00000568744 CYLD-016 50800679-50801930 retained_intron
  ENST00000569418 CYLD-001 50742050-50796881 protein_coding
  ENST00000569681 CYLD-011 50742050-50750197 protein_coding
  ENST00000569891 CYLD-004 50742070-50786781 retained_intron

Homo sapiens Ensembl GRCh38

Genome
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Sequences
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Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000398568ENST00000427738ENST00000564326ENST00000568704ENST00000569418ENST00000569891
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000398568 N/A 2.105±0.68 N/A 5.741±0.00 1.994±0.89
ENST00000427738 0.400±0.00 1.145±0.35 1.446±0.00 4.086±0.00 0.486±0.13
ENST00000564326 N/A 3.028±0.61 N/A 4.751±0.00 2.229±1.12
ENST00000568704 3.834±0.07 1.631±0.01 1.592±0.00 N/A N/A
ENST00000569418 N/A 3.175±1.39 N/A N/A 2.851±2.05
ENST00000569891 N/A 1.316±0.13 N/A N/A 0.645±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0007ON CIL_0007ON_0001 UCNEbase
CIL_00090I CIL_00090I_0001 VISTA
CIL_00085B CIL_00085B_0001 VISTA
CIL_00090J CIL_00090J_0001 VISTA
CIL_00090K CIL_00090K_0001 VISTA
CIL_00090L CIL_00090L_0001 VISTA
CIL_00090M CIL_00090M_0001 VISTA
CIL_0003PR CIL_0003PR_0001 CGP
CIL_00090N CIL_00090N_0001 VISTA
CIL_0008AU CIL_0008AU_0001 VISTA
CIL_00077S CIL_00077S_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004843 IDA ubiquitin-specific protease activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005813 IDA centrosome
GO:0005829 IDA cytosol
GO:0005881 IDA cytoplasmic microtubule
GO:0006511 IEA ubiquitin-dependent protein catabolic process
GO:0007049 IEA cell cycle
GO:0007346 IMP regulation of mitotic cell cycle
GO:0008270 IDA zinc ion binding
GO:0016055 IEA Wnt signaling pathway
GO:0016579 IEA protein deubiquitination
GO:0019901 IPI protein kinase binding
GO:0030496 IDA midbody
GO:0031234 IDA extrinsic component of cytoplasmic side of plasma membrane
GO:0032088 IDA negative regulation of NF-kappaB transcription factor activity
GO:0032480 TAS negative regulation of type I interferon production
GO:0035872 TAS nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway
GO:0036459 IEA ubiquitinyl hydrolase activity
GO:0042347 IDA negative regulation of NF-kappaB import into nucleus
GO:0045087 TAS innate immune response
GO:0045581 IEA negative regulation of T cell differentiation
GO:0061578 IDA Lys63-specific deubiquitinase activity
GO:0070064 IPI proline-rich region binding
GO:0070266 IBA necroptotic process
GO:0070423 TAS nucleotide-binding oligomerization domain containing signaling pathway
GO:0070507 IMP regulation of microtubule cytoskeleton organization
GO:0070536 IDA protein K63-linked deubiquitination
GO:0090090 IMP negative regulation of canonical Wnt signaling pathway
GO:1901026 IEA ripoptosome assembly involved in necroptotic process
GO:2001238 IMP positive regulation of extrinsic apoptotic signaling pathway
GO:2001242 IMP regulation of intrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000060058 cylda protein_coding Danio_rerio
ENSMUSG00000036712 Cyld protein_coding Mus_musculus

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