ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: amyloid beta (A4) precursor-like protein 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000084234 APLP2 9606 + 11:130069837-130144811 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000263574 APLP2-005 130069906-130144811 protein_coding
  ENST00000278756 APLP2-008 130070568-130144804 protein_coding
  ENST00000338167 APLP2-001 130069921-130144405 protein_coding
  ENST00000345598 APLP2-002 130069916-130143679 protein_coding
  ENST00000461918 APLP2-016 130108605-130109602 retained_intron
  ENST00000525215 APLP2-017 130109161-130110573 retained_intron
  ENST00000525604 APLP2-026 130141412-130144273 retained_intron
  ENST00000526330 APLP2-022 130069894-130122377 processed_transcript
  ENST00000527702 APLP2-020 130069894-130121766 processed_transcript
  ENST00000528499 APLP2-003 130069894-130143806 protein_coding
  ENST00000529235 APLP2-028 130069894-130120823 processed_transcript
  ENST00000529483 APLP2-030 130109427-130120817 processed_transcript
  ENST00000529701 APLP2-021 130069894-130122470 processed_transcript
  ENST00000530132 APLP2-010 130069894-130110560 nonsense_mediated_decay
  ENST00000530493 APLP2-025 130140495-130143434 retained_intron
  ENST00000532456 APLP2-029 130069837-130110637 processed_transcript
  ENST00000533195 APLP2-011 130069894-130110659 protein_coding
  ENST00000533532 APLP2-014 130069894-130109823 retained_intron
  ENST00000533616 APLP2-009 130069837-130143522 nonsense_mediated_decay
  ENST00000533618 APLP2-015 130069894-130120777 retained_intron
  ENST00000533713 APLP2-027 130069894-130120823 protein_coding
  ENST00000533860 APLP2-024 130138778-130143575 retained_intron
  ENST00000534001 APLP2-031 130069894-130121783 processed_transcript
  ENST00000534582 APLP2-018 130069894-130121726 nonsense_mediated_decay
  ENST00000534761 APLP2-023 130069891-130121718 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000263574ENST00000278756ENST00000338167ENST00000345598ENST00000528499ENST00000533616
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000263574 28.282±0.00 136.804±58.18 N/A 133.098±98.16
ENST00000278756 N/A 27.414±9.99 N/A 50.093±36.99
ENST00000338167 N/A N/A 255.205±0.00 N/A
ENST00000345598 N/A 247.878±0.00 N/A N/A
ENST00000528499 N/A 83.975±40.95 N/A 159.872±142.21
ENST00000533616 N/A 162.879±37.67 N/A 0.361±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_000511 CIL_000511_0002 CGP
CIL_000510 CIL_000510_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001967 IEA suckling behavior
GO:0003677 NAS DNA binding
GO:0004867 IEA serine-type endopeptidase inhibitor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005886 IEA plasma membrane
GO:0006878 IEA cellular copper ion homeostasis
GO:0007176 IEA regulation of epidermal growth factor-activated receptor activity
GO:0007186 NAS G-protein coupled receptor signaling pathway
GO:0007617 IEA mating behavior
GO:0007626 IEA locomotory behavior
GO:0008201 IEA heparin binding
GO:0008203 IEA cholesterol metabolic process
GO:0010951 IEA negative regulation of endopeptidase activity
GO:0016020 IDA membrane
GO:0016021 NAS integral component of membrane
GO:0030198 IEA extracellular matrix organization
GO:0030900 IEA forebrain development
GO:0030901 IEA midbrain development
GO:0042802 IPI identical protein binding
GO:0043393 IEA regulation of protein binding
GO:0046914 IEA transition metal ion binding
GO:0050885 IEA neuromuscular process controlling balance
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000054864 aplp2 protein_coding Danio_rerio
ENSMUSG00000031996 Aplp2 protein_coding Mus_musculus

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