ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: L-2-hydroxyglutarate dehydrogenase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000087299 L2HGDH 9606 - 14:50237563-50312548 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000261699 L2HGDH-002 50237563-50312168 protein_coding
  ENST00000267436 L2HGDH-001 50242434-50312548 protein_coding
  ENST00000421284 L2HGDH-003 50245651-50312229 protein_coding
  ENST00000554191 L2HGDH-005 50294198-50312226 nonsense_mediated_decay
  ENST00000555423 L2HGDH-004 50282443-50312226 protein_coding
  ENST00000555610 L2HGDH-007 50283853-50312154 protein_coding
  ENST00000556393 L2HGDH-006 50302017-50312147 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000267436ENST00000421284
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000267436 0.627±0.11 1.325±0.64 0.488±0.00 1.416±0.00 1.407±0.91
ENST00000421284 N/A 4.384±0.65 N/A N/A 1.339±0.77

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0005HL CIL_0005HL_0002 CGP
CIL_0005HM CIL_0005HM_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005739 IDA mitochondrion
GO:0005743 TAS mitochondrial inner membrane
GO:0006103 TAS 2-oxoglutarate metabolic process
GO:0016021 IDA integral component of membrane
GO:0016491 IEA oxidoreductase activity
GO:0031305 NAS integral component of mitochondrial inner membrane
GO:0044237 TAS cellular metabolic process
GO:0044267 IDA cellular protein metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0047545 IDA 2-hydroxyglutarate dehydrogenase activity
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000060500 l2hgdh protein_coding Danio_rerio
ENSMUSG00000020988 L2hgdh protein_coding Mus_musculus

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